ReviewFrontiers in plant science2018
NAD Kinases: Metabolic Targets Controlling Redox Co-enzymes and Reducing Power Partitioning in Plant Stress and Development.
Review in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 46 citations in OpenAlex.
- A WHY1-NADK3-PEX5 module confers drought tolerance by maintaining peroxisomal ROS homeostasis in Brassica napus.The Plant journal : for cell and molecular biology · 2026Article
- Genome-wide association study identifies consistent genomic loci for yield and nutritional quality in Ethiopian sorghum landraces.The plant genome · 2026Article
- Phyllosphere microbiome: Exploring the unexplored frontiers for precision agricultural and environmental sustainability.World journal of microbiology & biotechnology · 2026Review
- Plant responses to gaseous pollutants, biochemical and transcriptomic insights.Frontiers in plant science · 2026Review
- NAD(H) and NADP(H) in plants and mammals.Molecular plant · 2025Review
- An Optimized Editing Approach for Wheat Genes by Improving sgRNA Design and Transformation Strategies.International journal of molecular sciences · 2025Article
- NADK as a molecular marker to distinguish between alcohol- and non-alcohol-associated liver cirrhosis: A pilot study.Clinical and experimental hepatology · 2025Article
- Identification of novel candidate genes for regulating oil composition in soybean seeds under environmental stresses.Frontiers in plant science · 2025Article
- Microbial survival strategies in desiccated roots ofFrontiers in microbiology · 2025Article
- Structure-based design, synthesis and biological evaluation of a NADThe FEBS journal · 2023Article
- Involvement of Calcium and Calmodulin in NO-Alleviated Salt Stress in Tomato Seedlings.Plants (Basel, Switzerland) · 2022Article
- Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- NAD kinase promoteseLife · 2022Article
- Taxonomic distribution and evolutionary analysis of the equol biosynthesis gene cluster.BMC genomics · 2022Article
- Mitochondrial NADMolecular cell · 2021Article
- The CaFrontiers in plant science · 2021Article
- Novel Genes and Genetic Loci Associated With Root Morphological Traits, Phosphorus-Acquisition Efficiency and Phosphorus-Use Efficiency in Chickpea.Frontiers in plant science · 2021Article
- NAD metabolism in aging and cancer.Experimental biology and medicine (Maywood, N.J.) · 2020Article
- In Vivo NADH/NADThe Plant cell · 2020Article
- The NAD kinase OsNADK1 affects the intracellular redox balance and enhances the tolerance of rice to drought.BMC plant biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
NAD(H) and NADP(H) are essential co-enzymes which dominantly control a number of fundamental biological processes by acting as reducing power and maintaining the intracellular redox balance of all life kingdoms. As the only enzymes that catalyze NAD(H) and ATP to synthesize NADP(H), NAD Kinases (NADKs) participate in many essential metabolic reactions, redox sensitive regulation, photosynthetic performance and also reactive oxygen species (ROS) homeostasis of cells and therefore, play crucial roles in both development and stress responses of plants. NADKs are highly conserved enzymes in amino acid sequences but have multiple subcellular localization and diverse functions. They may function as monomers, dimers or multimers in cells but the enzymatic properties in plants are not well elucidated yet. The activity of plant NADK is regulated by calcium/calmodulin and plays crucial roles in photosynthesis and redox co-enzyme control. NADK genes are expressed in almost all tissues and developmental stages of plants with specificity for different members. Their transcripts can be greatly stimulated by a number of environmental factors such as pathogenic attack, irritant applications and abiotic stress treatments. Using transgenic approaches, several studies have shown that NADKs are involved in chlorophyll synthesis, photosynthetic efficiency, oxidative stress protection, hormone metabolism and signaling regulation, and therefore contribute to the growth regulation and stress tolerance of plants. In this review, the enzymatic properties and functional mechanisms of plant NADKs are thoroughly investigated based on literature and databases. The results obtained here are greatly advantageous for further exploration of NADK function in plants.
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