Evidence map›Paper›PMID 29662326›Full record

ArticleCancer growth and metastasis2018

CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche.

Lynn Roy, Alexander Bobbs, Rachel Sattler, Jeffrey L Kurkewich, Paige B Dausinas, Prakash Nallathamby, Karen D Cowden Dahl

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer growth and metastasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lynn RoyHarper Cancer Research Institute, South Bend, IN, USA.
Alexander BobbsHarper Cancer Research Institute, South Bend, IN, USA.
Rachel SattlerHarper Cancer Research Institute, South Bend, IN, USA.
Jeffrey L KurkewichHarper Cancer Research Institute, South Bend, IN, USA.
Paige B DausinasHarper Cancer Research Institute, South Bend, IN, USA.
Prakash NallathambyDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, USA.
Karen D Cowden DahlHarper Cancer Research Institute, South Bend, IN, USA.
Mike and Josie Harper Cancer Research InstituteUniversity of Notre Dame · USIndiana University – Purdue University Indianapolis · USIndiana University South Bend · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) are an attractive therapeutic target due to their predicted role in both metastasis and chemoresistance. One of the most commonly agreed on markers for ovarian CSCs is the cell surface protein CD133. CD133+ ovarian CSCs have increased tumorigenicity, resistance to chemotherapy, and increased metastasis. Therefore, we were interested in defining how CD133 is regulated and whether it has a role in tumor metastasis. Previously we found that overexpression of the transcription factor,

Indexed as

adhesioncancer stem cellsmetastasisOvarian cancertranscription factor

Identifiers

PMID29662326
PMCPMC5894897
OpenAlexW2798002441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.