ArticleInternational journal of nanomedicine2018
Nanoselenium prevents eimeriosis-induced inflammation and regulates mucin gene expression in mice jejunum.
Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 59 citations in OpenAlex.
- Therapeutic potential of greenly synthesized selenium nanoparticles against experimental cyclosporiasis.Scientific reports · 2025Article
- The impact of plasma-activated water and selenium nanoparticle solution on the shelf life of Mandarin cv. Orlando Tangelo in storage.Scientific reports · 2025Article
- Effect of selenium nanoparticles on intestinal immunity through regulation of NLRP3 signaling pathway.Scientific reports · 2025Article
- The ameliorative effect of selenium-loaded chitosan nanoparticles against silver nanoparticles-induced ovarian toxicity in female albino rats.Journal of ovarian research · 2025Article
- Selenium nanoparticle inclusion in broiler diets for enhancing sustainable production and health.Scientific reports · 2024Article
- Thiolated chitosan nanoparticles encapsulated nisin and selenium: antimicrobial/antibiofilm/anti-attachment/immunomodulatory multi-functional agent.BMC microbiology · 2024Article
- Advances in Nrf2 Signaling Pathway by Targeted Nanostructured-Based Drug Delivery Systems.Biomedicines · 2024Review
- Persea americana extract protects intestinal tissue from Eimeria papillata-induced murine Infection.BMC veterinary research · 2023Article
- Biogenic Selenium Nanoparticles in Biomedical Sciences: Properties, Current Trends, Novel Opportunities and Emerging Challenges in Theranostic Nanomedicine.Nanomaterials (Basel, Switzerland) · 2023Review
- Nano selenium-enriched probioticFrontiers in immunology · 2023Article
- Biosynthesized selenium nanoparticles to rescue coccidiosis-mediated oxidative stress, apoptosis and inflammation in the jejunum of mice.Frontiers in immunology · 2023Article
- Supplementation of Selenium Nanoparticles-Loaded Chitosan Improves Production Performance, Intestinal Morphology, and Gut Microflora in Broiler Chickens.The journal of poultry science · 2022Article
- Toxicological effects of nanoselenium in animals.Journal of animal science and biotechnology · 2022Review
- Anticoccidial activity of natural plants extracts mixture againstFrontiers in veterinary science · 2022Article
- Selenium Nanoparticles Improved Intestinal Health Through Modulation of the NLRP3 Signaling Pathway.Frontiers in nutrition · 2022Article
- Selenium and protozoan parasitic infections: selenocompounds and selenoproteins potential.Parasitology research · 2022Review
- The Advancing of Selenium Nanoparticles Against Infectious Diseases.Frontiers in pharmacology · 2021Review
- Article
- Selenium as a pleiotropic agent for medical discovery and drug delivery.International journal of nanomedicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough elemental selenium has been found to be effective against
methodsThe mice were divided into 4 groups, with the first being the non-infected, control group, and the second, third, and fourth groups being orally inoculated with 1,000 sporulated oocysts of
resultsThe infection induced severe histopathological jejunal damage, reflected in the form of destroyed jejunal mucosa, increased jejunal oxidative damage, a reduction in the number of jejunal goblet cells, and increased production of pro-inflammatory cytokines, quantified by real-time polymerase chain reaction. Treatment of mice with SeNPs significantly decreased the oocyst output in the feces by ~80%. Furthermore, the number of parasitic stages counted in stained jejunal paraffin sections was significantly decreased after the mice were treated with SeNPs. In addition, the number of goblet cells increased from 42.6±7.3 to 95.3±8.5 cells/10 villus-crypt units after treatment. By day 5 post-infection with
conclusionThe results collectively showed that SeNPs are more effective than sodium selenite with regard to their anti-coccidial, anti-oxidant, and anti-inflammatory role against eimeriosis induced in the jejunum of mice.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.