Evidence map›Paper›PMID 29662272›Full record

ArticleShock waves2018

Effect of bulk modulus on deformation of the brain under rotational accelerations.

S Ganpule, N P Daphalapurkar, M Pirtini Cetingul, K T Ramesh

Open access · greenAbstract read
In one paragraph

Article in Shock waves, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Journal of the Royal Society, Interface · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

S GanpuleIndian Institute of Technology Roorkee, Roorkee, India, 247667.
N P DaphalapurkarHopkins Extreme Materials Institute, Johns Hopkins University, Baltimore, MD, 21218.
M Pirtini CetingulGeneral Electric Healthcare Maternal-Infant Care, Laurel, MD, 20723.
K T RameshHopkins Extreme Materials Institute, Johns Hopkins University, Baltimore, MD, 21218.
Johns Hopkins University · USGeneral Electric (United States) · USIndian Institute of Technology Roorkee · IN

Funding

IN VIVO MEASUREMENT OF BRAIN BIOMECHANICSR01NS055951 · NINDS · WASHINGTON UNIVERSITY · PI BAYLY, PHILIP V · 2007 to 2017
$3.9M
NINDS NIH HHS R01 NS055951
6 · The paper itself

Abstract

Traumatic brain injury such as that developed as a consequence of blast is a complex injury with a broad range of symptoms and disabilities. Computational models of brain biomechanics hold promise for illuminating the mechanics of traumatic brain injury (TBI) and for developing preventive devices. However, reliable material parameters are needed for models to be predictive. Unfortunately, the properties of human brain tissue are difficult to measure, and the bulk modulus of brain tissue in particular is not well-characterized. Thus, a wide range of bulk modulus values are used in computational models of brain biomechanics, spanning up to three orders of magnitude in the differences between values. However, the sensitivity of these variations on computational predictions is not known. In this work, we study the sensitivity of a 3D computational human head model to various bulk modulus values. A subject-specific human head model was constructed from T1-weighted MRI images at 2 mm

Indexed as

Brain bulk moduluscomparison of strain fieldscomputational head modelin vivo brain deformationprediction of injury

Identifiers

PMID29662272
PMCPMC5898454
OpenAlexW2779308992

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.