Evidence map›Paper›PMID 29662232›Full record

ArticleScientific reports2018

Characterization of AiiK, an AHL lactonase, from Kurthia huakui LAM0618

Weiwei Dong, Jie Zhu, Xiang Guo, Delong Kong, Qi Zhang, Yiqing Zhou, Xiaoyang Liu, Shumiao Zhao, Zhiyong Ruan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  7. MzmL, a novel marine derivedFrontiers in microbiology · 2024
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  8. Article
  9. Article
  10. Review
  11. Review
  12. Pseudomonas aeruginosa Quorum Sensing.Advances in experimental medicine and biology · 2022
    Article
  13. Novel Quorum Quenching YtnP Lactonase FromFrontiers in microbiology · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Weiwei DongState Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Jie ZhuCollege of life science, Xinjiang Normal University, Xinjiang, 830046, China.
Xiang GuoInstitute of Agricultural Resources and Regional Planning, CAAS, Beijing, 100081, China.
Delong KongInstitute of Agricultural Resources and Regional Planning, CAAS, Beijing, 100081, China.
Qi ZhangCollege of life science, Xinjiang Normal University, Xinjiang, 830046, China.
Yiqing ZhouInstitute of Agricultural Resources and Regional Planning, CAAS, Beijing, 100081, China.
Xiaoyang LiuInstitute of Agricultural Resources and Regional Planning, CAAS, Beijing, 100081, China.
Shumiao ZhaoState Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. shumiaozhao@mail.hzau.edu.cn.
Zhiyong RuanInstitute of Agricultural Resources and Regional Planning, CAAS, Beijing, 100081, China. ruanzhiyong@caas.cn.
Institute of Agricultural Resources and Regional Planning · CNHuazhong Agricultural University · CNXinjiang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-Acyl homoserine lactones (AHLs) act as the key quorum sensing (QS) signal molecules in gram-negative bacteria, which coordinates gene expression and then activates various processes, including biofilm formation and production of virulence factors in some pathogens. Quorum quenching (QQ), which is the inactivation of the signal molecules by means of enzymatic degradation or modification, inhibits the processes of QS rather than killing the pathogens and is a promising antipathogenic strategy to control the bacterial pathogens. In this study, an AHL lactonase gene (named aiiK) was cloned from Kurthia huakuii LAM0618

Indexed as

Quorum SensingAcyl-ButyrolactonesBacterial ProteinsCarboxylic Ester HydrolasesCloning, MolecularGene Expression Regulation, BacterialHydrolysisPlanococcaceaePseudomonas aeruginosaPyocyanineSubstrate SpecificityAcyl-ButyrolactonesBacterial ProteinsCarboxylic Ester HydrolasesN-acyl homoserine lactonasePyocyanine

Identifiers

PMID29662232
PMCPMC5902575
OpenAlexW2803722207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.