ArticleNature communications2018
Variation in Wolbachia effects on Aedes mosquitoes as a determinant of invasiveness and vectorial capacity.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 66 citations in OpenAlex.
- Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence.Environmental microbiology · 2026Article
- Metabolic characteristics in orthoflaviviral infections: unveiling pathogenic mechanisms and therapeutic targets.Virology journal · 2025Review
- The Symbiotic Bacterial Profile of Laboratory-Reared and Field-CaughtMicroorganisms · 2025Article
- Strain-specific quantification ofFrontiers in insect science · 2025Article
- Detecting and quantifying heterogeneity in susceptibility using contact tracing data.PLoS computational biology · 2024Article
- Article
- Is there a sicker sex? Dose relationships modify male-female differences in infection prevalence.Proceedings. Biological sciences · 2024Article
- Profiling lipidomic changes in dengue-resistant and dengue-susceptible strains of Colombian Aedes aegypti after dengue virus challenge.PLoS neglected tropical diseases · 2023Article
- Article
- UsingFrontiers in microbiology · 2023Review
- Interspecies Isobaric Labeling-Based Quantitative Proteomics Reveals Protein Changes in the Ovary ofFrontiers in cellular and infection microbiology · 2022Article
- Combating mosquito-borne diseases using genetic control technologies.Nature communications · 2021Review
- Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported.Nature communications · 2020Article
- Reply to: "Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported".Nature communications · 2020Article
- The Aedes albopictus (Diptera: Culicidae) microbiome varies spatially and with Ascogregarine infection.PLoS neglected tropical diseases · 2020Article
- Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: A case study in the Amazon Basin.PLoS computational biology · 2020Article
- Mosquito Microbiota and Implications for Disease Control.Trends in parasitology · 2020Review
- Article
- The Challenges of Microbial Control of Mosquito-Borne Diseases Due to the Gut Microbiome.Frontiers in genetics · 2020Review
- Heatwaves cause fluctuations in wMel Wolbachia densities and frequencies in Aedes aegypti.PLoS neglected tropical diseases · 2020Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wolbachia has been introduced into Aedes aegypti mosquitoes to control the spread of arboviruses, such as dengue, chikungunya and Zika. Studies showed that certain Wolbachia strains (such as wMel) reduce replication of dengue viruses in the laboratory, prompting the release of mosquitoes carrying the bacterium into the field, where vectorial capacity can be realistically assessed in relation to native non-carriers. Here we apply a new analysis to two published datasets, and show that wMel increases the mean and the variance in Ae. aegypti susceptibility to dengue infection when introgressed into Brazil and Vietnam genetic backgrounds. In the absence of other processes, higher mean susceptibility should lead to enhanced viral transmission. The increase in variance, however, widens the basis for selection imposed by unexplored natural forces, retaining the potential for reducing transmission overall.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.