ArticleNature communications2018
μ-opioid receptor system mediates reward processing in humans.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 112 citations in OpenAlex.
- Effects of dopamine and opioid receptor antagonism on the neural processing of social and nonsocial rewards.Human brain mapping · 2024Trial
- Mitragynine reduces methamphetamine self-administration in rats without disrupting food-maintained responding.Psychopharmacology · 2026Article
- Naltrexone/bupropion for binge-eating disorder: A human laboratory investigation of mechanisms.Drug and alcohol dependence reports · 2026Article
- Endogenous opioid system modulates proximal and distal threat signals in the human brain.Molecular psychiatry · 2026Article
- Chewing function, diet quality, and risk of metabolic syndrome and mortality: analysis of NHANES 1999-2018.BMC oral health · 2026Article
- A Personalized Medicine Approach: Psychosocial and Genetic Risk Assessments Predictors of Bariatric Surgery Outcomes After 3 Years.Biomedicines · 2026Article
- PET Molecular Imaging of the Endocannabinoid System in Psychiatric Disorders.Neuroscience bulletin · 2026Review
- Neurobiological Consequences of High-Fat High-Sugar Diets on the Mesocorticolimbic System: a Narrative Review.Current nutrition reports · 2026Review
- Exercise intervention modulates food reward in obesity: efficacy, mechanisms, and prospects.Frontiers in nutrition · 2026Article
- New Antidepressant Development in the Treatment of Depression.Advances in experimental medicine and biology · 2026Review
- Brain cannabinoid CB1 receptor signaling modulates reward responses and inhibitory control in humans.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Dark seasons enhance brain and brown adipose tissue interactions related to mu-opioid receptor signaling.European journal of nuclear medicine and molecular imaging · 2025Article
- Pleasurable music activates cerebral µ-opioid receptors: a combined PET-fMRI study.European journal of nuclear medicine and molecular imaging · 2025Article
- Unravelling the genetic and molecular basis of low-frequency rTMS induced changes in functional connectivity density in schizophrenia patients with auditory verbal hallucinations.Translational psychiatry · 2025Article
- Anorexia nervosa is associated with higher brain mu-opioid receptor availability.Molecular psychiatry · 2025Article
- Oxytocin and opioid antagonists: A dual approach to improving social behavior.Annals of the New York Academy of Sciences · 2025Review
- Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development.Neuron · 2025Article
- Endogenous opioid receptors and the feast or famine of maladaptive feeding.Nature communications · 2025Review
- Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development.bioRxiv : the preprint server for biology · 2025Article
- Utilization of a precision medicine genetic and psychosocial approach in outcome assessment of bariatric weight loss surgery: a narrative review.Frontiers in public health · 2025Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endogenous μ-opioid receptor (MOR) system regulates motivational and hedonic processing. We tested directly whether individual differences in MOR are associated with neural reward responses to food pictures in humans. We scanned 33 non-obese individuals with positron emission tomography (PET) using the MOR-specific radioligand [
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.