ArticleInternational journal of environmental research and public health2018
Cardiovascular-Related Outcomes in U.S. Adults Exposed to Lead.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 71 citations in OpenAlex.
- Environmental Toxic Metals and Metalloids Exposure and Cardiovascular Health: Current Evidence from Oxidative Stress and Inflammatory Biomarkers as Indicators of Subclinical Cardiovascular Effects.Antioxidants (Basel, Switzerland) · 2026Review
- Association between heavy metal exposure and high-sensitivity C-reactive protein in the elderly: Korea National Health and Nutrition Examination Survey (KNHANES) 2016-2017.Annals of occupational and environmental medicine · 2026Article
- Combined Effects of Environmental Metals and Physiological Stress on Lipid Dysregulation.Medical sciences (Basel, Switzerland) · 2024Article
- Investigating the Interplay of Toxic Metals and Essential Elements in Liver Disease.International journal of environmental research and public health · 2024Article
- Association of Combined PFOA, PFOS, Metals and Allostatic Load on Hepatic Disease Risk.Journal of xenobiotics · 2024Article
- Contamination and Carcinogenic Risks of Lead in Lip Cosmetics in China.Bulletin of environmental contamination and toxicology · 2024Article
- Involvement of Nrf2 Signaling in Lead-induced Toxicity.Current medicinal chemistry · 2024Review
- Article
- Potential diagnostic biomarkers for lead-induced hepatotoxicity and the role of synthetic chelators and bioactive compounds.Toxicology research · 2023Review
- The New Hyperspectral Analysis Method for Distinguishing the Types of Heavy Metal Copper and Lead Pollution Elements.International journal of environmental research and public health · 2022Article
- True Colors: Unmasking Hidden Lead in Cosmetics from Low- and Middle-Income Countries.Environmental health perspectives · 2022Article
- Inflammatory Cells in Atherosclerosis.Antioxidants (Basel, Switzerland) · 2022Review
- Mapping the Morbidity Risk Associated with Coal Mining in Queensland, Australia.International journal of environmental research and public health · 2022Article
- Blood Lead and High-Density Lipoprotein Concentrations in Relation to Human Blood Pressure: A Cross Sectional Study.Frontiers in nutrition · 2022Article
- Association between blood lead levels and hyperlipidemiais: Results from the NHANES (1999-2018).Frontiers in public health · 2022Article
- Article
- Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality-A Preliminary Study.International journal of environmental research and public health · 2021Article
- Association between cumulative childhood blood lead exposure and hepatic steatosis in young Mexican adults.Environmental research · 2021Article
- Lead Distribution in Urban Soil in a Medium-Sized City: Household-Scale Analysis.Environmental science & technology · 2021Article
- Higher Blood Lead Level Is Associated With Increased Likelihood of Abdominal Aortic Calcification.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular-related clinical markers were evaluated in this cross-sectional study of United States adults (aged ≥ 20) exposed to lead via the National Health and Nutrition Examination Survey 2007-2008 and the 2009-2010 datasets. In four quartiles of exposure-0-2 μg/dL, 2-5 μg/dL, 5-10 μg/dL, and 10 μg/dL and over, clinical and anthropometric markers were evaluated-to examine how the markers manifested in the quartiles. Associations were determined via linear regression. Finally, clinical makers, and how they manifested between exposed and less-exposed occupations, were explored in addition to how duration of exposure altered these clinical markers. In regression analysis, Diastolic Blood Pressure (DBP) and high-density lipoprotein (HDL) cholesterol, were significantly associated with blood lead level (BLL). In the occupational analysis, Systolic Blood Pressure (SBP), DBP, C-reactive protein (CRP), triglycerides, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, showed differences between populations in the exposed and less-exposed occupations. Regarding Agriculture, Forestry & Fishing, the duration of exposure altered SBP, CRP, and LDL cholesterol. With mining, the duration of exposure altered SBP, DBP, triglycerides, and HDL cholesterol, whereas in construction, the duration in occupation altered SBP, triglycerides, and CRP. In conclusion, lead exposure has a profound effect on the cardiovascular system, with potentially adverse outcomes existing at all exposure levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.