Evidence map›Paper›PMID 29661910›Full record

ArticleEMBO molecular medicine2018

Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity.

Dayanira Alsina-Beauchamp, Alejandra Escós, Pilar Fajardo, Diego González-Romero, Ester Díaz-Mora, Ana Risco, Miguel A Martín-Serrano, Carlos Del Fresno, Jorge Dominguez-Andrés, Noelia Aparicio and 8 more

Open access · goldAbstract read
In one paragraph

Article in EMBO molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. p38γ and p38δ MAP kinases in inflammation.Biochemical Society transactions · 2026
    Review
  2. Loss of Fgr41 inInfection and immunity · 2026
    Article
  3. p38γ and p38δ support CD4Frontiers in immunology · 2026
    Article
  4. Review
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  6. Article
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  14. TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 withProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. CD200 ModulatesInternational journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Dayanira Alsina-BeauchampDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Alejandra EscósDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.ORCID 0000-0002-2990-7920
Pilar FajardoDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Diego González-RomeroDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Ester Díaz-MoraDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Ana RiscoDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Miguel A Martín-SerranoDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Carlos Del FresnoImmunobiology of Inflammation Laboratory Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Jorge Dominguez-AndrésDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Noelia AparicioDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Rafal ZurDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Natalia ShpiroMedical Research Council Protein Phosphorylation Unit, Sir James Black Building, School of Life Sciences, University of Dundee, Dundee, UK.
Gordon D BrownAberdeen Fungal Group, Institute of Medical Sciences, Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen, UK.
Carlos ArdavínDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Mihai G NeteaDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Susana AlemanyInstituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid, Spain.
Juan J Sanz-EzquerroDepartment of Cellular and Molecular Biology, CNB/CSIC, Madrid, Spain.
Ana CuendaDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain acuenda@cnb.csic.es.ORCID 0000-0002-9013-5077
Centro Nacional de Biotecnología · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ESRadboud University Nijmegen · NLSpanish National Centre for Cardiovascular Research · ESUniversity of Aberdeen · GBUniversity of Dundee · GB

Funding

European Research Council 310372Medical Research Council MR/N006364/1Wellcome Trust 102705Wellcome Trust 102705/Z/13/ZWellcome Trust 97377
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCandida albicansCandidiasisFemaleHost-Pathogen InteractionsMacrophagesMice, Inbred C57BLMice, KnockoutMitogen-Activated Protein Kinase 12Mitogen-Activated Protein Kinase 13Myeloid CellsNeutrophilsNitric Oxide Synthase Type IIReactive Oxygen SpeciesSignal TransductionMitogen-Activated Protein Kinase 12Mitogen-Activated Protein Kinase 13Nitric Oxide Synthase Type IIReactive Oxygen SpeciesCandida albicansinfectionkinase inhibitorp38MAPKsignalling

Identifiers

PMID29661910
PMCPMC5938613
OpenAlexW2799726203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.