Evidence map›Paper›PMID 29661847›Full record

ArticleJournal of cell science2018

The Ajuba family protein Wtip regulates actomyosin contractility during vertebrate neural tube closure.

Chih-Wen Chu, Bo Xiang, Olga Ossipova, Andriani Ioannou, Sergei Y Sokol

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Linking Planar Cell Polarity to Mechanotransduction During Morphogenesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Emerging role of lipid metabolism alterations in Cancer stem cells.Journal of experimental & clinical cancer research : CR · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chih-Wen ChuDepartment of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Bo XiangDepartment of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Olga OssipovaDepartment of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Andriani IoannouDepartment of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sergei Y SokolDepartment of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA sergei.sokol@mssm.edu.ORCID 0000-0002-3963-9202
Icahn School of Medicine at Mount Sinai · US

Funding

Regulation of cell polarity by Wnt signalingR35GM122492 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Sergei Sokol · 2017 to 2026
$5.0M
NIGMS NIH HHS R35 GM122492
6 · The paper itself

Abstract

Ajuba family proteins are implicated in the assembly of cell junctions and have been reported to antagonize Hippo signaling in response to cytoskeletal tension. To assess the role of these proteins in actomyosin contractility, we examined the localization and function of Wtip, a member of the Ajuba family, in

Indexed as

ActinsActomyosinAdaptor Proteins, Signal TransducingAnimalsHumansMicrofilament ProteinsMultigene FamilyNeural TubeProtein BindingProtein DomainsTranscription FactorsXenopusXenopus ProteinsActinsActomyosinAdaptor Proteins, Signal TransducingMicrofilament ProteinsTranscription Factorswtip protein, XenopusXenopus ProteinsApical constrictionJunctionsShroom3TensionWilms tumor-1-interacting proteinXenopus

Identifiers

PMID29661847
PMCPMC6031329
OpenAlexW2802186993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.