Evidence map›Paper›PMID 29661831›Full record

ArticleCancer research2018

Differential Effects of Estrogen Receptor β Isoforms on Glioblastoma Progression.

Jinyou Liu, Gangadhara R Sareddy, Mei Zhou, Suryavathi Viswanadhapalli, Xiaonan Li, Zhao Lai, Rajeshwar R Tekmal, Andrew Brenner, Ratna K Vadlamudi

Open access · greenAbstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 77 citations in OpenAlex.

  1. Estrogen Receptor Beta Isoforms Interplay Integrates Nuclear and Extra-Nuclear Signaling to Modulate Human Granulosa Cell Growth.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. G-protein coupled estrogen receptor 1Frontiers in endocrinology · 2026
    Article
  6. Review
  7. Article
  8. Spatiotemporally Controlled T-Cell Combination Therapy for Solid Tumor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Therapeutic Applications of the CRISPR-Cas System.Bioengineering (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jinyou Liu *Department of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Gangadhara R Sareddy *Department of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Mei ZhouDepartment of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Suryavathi ViswanadhapalliDepartment of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Xiaonan LiDepartment of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Zhao LaiGreehey Children's Cancer Research Institute, San Antonio, Texas.
Rajeshwar R TekmalDepartment of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas.
Andrew BrennerMays Cancer Center, University of Texas Health at San Antonio, San Antonio, Texas.
Ratna K VadlamudiDepartment of Obstetrics and Gynecology, University of Texas Health at San Antonio, San Antonio, Texas. vadlamudi@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · USCentral South University · CNChildren's Cancer Center · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
Novel ERbeta agonists for the treatment of gliomasR01CA178499 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BRENNER, ANDREW JACOB, VADLAMUDI, RATNA K · 2014 to 2018
$1.6M
Orbitrap XL/ETD Mass SpectrometerS10RR025111 · NCRR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI WEINTRAUB, SUSAN T · 2009 to 2009
$776k
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
NCI NIH HHS P30 CA054174NCI NIH HHS R01 CA178499NCRR NIH HHS S10 RR025111NIH HHS S10 OD021805
6 · The paper itself

Abstract

The estrogen receptor β (ERβ) functions as a tumor suppressor in glioblastoma (GBM) cells. However, the

Indexed as

AnimalsBrainBrain NeoplasmsCRISPR-Cas SystemsDisease ProgressionEstrogen Receptor betaGene Knock-In TechniquesGene Knockout TechniquesGlioblastomaHumansMaleMiceMice, NudePrimary Cell CultureProtein IsoformsSurvival AnalysisESR2 protein, humanEstrogen Receptor betaProtein Isoforms

Identifiers

PMID29661831
PMCPMC6004261
OpenAlexW2803100310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.