Trial reportBMC public health2018
Breaking bad habits by improving executive function in individuals with obesity.
Trial report in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
Multidisciplinary Intervention and Cognitive Remediation Therapy for Adults With Obesity: Study Protocol for a Randomized Controlled Trial
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Loss of control as a transdiagnostic feature in obesity-related eating behaviours: A systematic review.European eating disorders review : the journal of the Eating Disorders Association · 2023Pooled it
- The Executive Functions in Overweight and Obesity: A Systematic Review of Neuropsychological Cross-Sectional and Longitudinal Studies.Frontiers in psychology · 2019Pooled it
- Adolescent sleep restriction, macronutrient consumption, and self-reported hunger: A randomized clinical trial.Clinical nutrition (Edinburgh, Scotland) · 2026Trial
- Cognitive remediation therapy (CRT-O) for young Indian adults living with overweight or obesity: a qualitative study of participant experience.Eating and weight disorders : EWD · 2026Trial
- Psychological and Behavioral Predictors of Weight Loss in the Reach Ahead for Lifestyle and Health-Diabetes Lifestyle Intervention Cohort.Journal of the Academy of Nutrition and Dietetics · 2023Trial
- Executive Function-Related Improvements on a Commercial CBT-Based Weight Management Intervention: Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- A Visualization Analysis of Hotspots and Frontiers in Obesity-Related Executive Functions Research: A Bibliometric Study.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- The interplay between executive functions and updating predictive representations.Scientific reports · 2025Article
- Caffeine: a potential mechanism for anti-obesity.Purinergic signalling · 2025Review
- The Impact of Different Types of Exercise on Executive Functions in Overweight/Obese Individuals: A Systematic Review and Network Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2024Review
- The Effect of Physical Activity Interventions on Executive Function in Overweight and Obese Adults: A Systematic Review.Biomedicines · 2024Review
- Multimodal Strategies to Fight Obesity: Research on Tailored Therapies Based on Natural and Synthetic Compounds for Prevention, Management and Treatment.International journal of molecular sciences · 2023Article
- Multidisciplinary intervention and cognitive remediation therapy for adults with obesity: A study protocol for a randomized controlled clinical trial.Contemporary clinical trials communications · 2023Article
- The mediating role of executive function in the relationship between self-stigma and self-injury or suicidal ideation among men who have sex with men living with HIV.Frontiers in public health · 2022Article
- Mediation by Executive Functions in the Associations Between Perceived Stress, Prenatal Distress, Emotional Control, and Dietary Intake in Overweight or Obese Pregnant Women.Journal of pediatrics, perinatology and child health · 2022Article
- Targeting executive function for weight loss in adults with overweight or obesity.Physiology & behavior · 2021Article
- Verbal memory is associated with adherence to COVID-19 protective behaviors in community dwelling older adults.Aging clinical and experimental research · 2021Article
- Cognitive disinhibition and infrequent moderate-to-intense physical activity linked with obesity in U.S. soldiers.Eating and weight disorders : EWD · 2021Article
- Cognitive remediation-enabled cognitive behaviour therapy for obesity: a case series.Eating and weight disorders : EWD · 2021Article
- A Conceptual Model of Long-Term Weight Loss Maintenance: The Importance of Cognitive, Empirical and Computational Approaches.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTwo primary factors that contribute to obesity are unhealthy eating and sedentary behavior. These behaviors are particularly difficult to change in the long-term because they are often enacted habitually. Cognitive Remediation Therapy has been modified and applied to the treatment of obesity (CRT-O) with preliminary results of a randomized controlled trial demonstrating significant weight loss and improvements in executive function. The objective of this study was to conduct a secondary data analysis of the CRT-O trial to evaluate whether CRT-O reduces unhealthy habits that contribute to obesity via improvements in executive function.
methodEighty participants with obesity were randomized to CRT-O or control. Measures of executive function (Wisconsin Card Sort Task and Trail Making Task) and unhealthy eating and sedentary behavior habits were administered at baseline, post-intervention and at 3 month follow-up.
resultsParticipants receiving CRT-O demonstrated improvements in both measures of executive function and reductions in both unhealthy habit outcomes compared to control. Mediation analyses revealed that change in one element of executive function performance (Wisconsin Card Sort Task perseverance errors) mediated the effect of CRT-O on changes in both habit outcomes.
conclusionThese results suggest that the effectiveness of CRT-O may result from the disruption of unhealthy habits made possible by improvements in executive function. In particular, it appears that cognitive flexibility, as measured by the Wisconsin Card Sort task, is a key mechanism in this process. Improving cognitive flexibility may enable individuals to capitalise on interruptions in unhealthy habits by adjusting their behavior in line with their weight loss goals rather than persisting with an unhealthy choice.
trial registrationThe RCT was registered with the Australian New Zealand Registry of Clinical Trials (trial id: ACTRN12613000537752 ).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.