Evidence map›Paper›PMID 29661150›Full record

ArticleBMC cardiovascular disorders2018

A moderate 500-m treadmill walk for estimating peak oxygen uptake in men with NYHA class I-II heart failure and reduced left ventricular ejection fraction.

Gianni Mazzoni, Biagio Sassone, Giovanni Pasanisi, Jonathan Myers, Simona Mandini, Stefano Volpato, Francesco Conconi, Giorgio Chiaranda, Giovanni Grazzi

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05817305 (Efficacy of an Exercise-based Secondary Prevention Program in Patients With Stable Cardiovascular Disease), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05817305 recruitingnot on this map

Efficacy of an Exercise-based Secondary Prevention Program in Patients With Stable Cardiovascular Disease

Typeobservational_patient_registrySponsorUniversità degli Studi di FerraraRan1997 to 2047Enrolled5,000ConditionsCardiovascular Diseases, Physical Inactivity, Aging, Quality of LifeArmsMedical history and functional evaluation, Health education
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. The body weight-walking distance product as a superior parameter in determining the VO2 on-kinetics in coronary artery disease.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gianni MazzoniDepartment of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
Biagio SassoneDepartment of Medicine, Division of Cardiology, Cento Hospital, AUSL Ferrara, Ferrara, Italy.
Giovanni PasanisiDepartment of Medicine, Division of Cardiology, "Delta" Hospital, AUSL Ferrara, Ferrara, Italy.
Jonathan MyersVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.
Simona MandiniCenter of Biomedical Studies Applied to Sport, University of Ferrara, via Gramicia 35 -, 44123, Ferrara, Italy. simona.mandini@unife.it.ORCID 0000-0001-8569-6702
Stefano VolpatoDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Francesco ConconiCenter of Biomedical Studies Applied to Sport, University of Ferrara, via Gramicia 35 -, 44123, Ferrara, Italy.
Giorgio ChiarandaGeneral Directorship for Public Health and Integration Policy, Emilia-Romagna Region, Bologna, Italy.
Giovanni GrazziDepartment of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaximal cardiopulmonary exercise testing (CPX) is the gold-standard for cardiorespiratory fitness assessment in chronic heart failure (CHF) patients. However, high costs, required medical supervision, and safety concerns make maximal exercise testing impractical for evaluating mobility-impaired adults. Thus, several submaximal walking protocols have been developed and currently used to estimate peak oxygen consumption (VO

methodsForty-three clinically stable men with HFrEF (age 67.7 ± 9.2 years, and left ventricular ejection fraction, LVEF 38% ± 6%) underwent exercise testing during an outpatient cardiac rehabilitation/secondary prevention program. Each patients completed a CPX, and a moderate and self-paced (11-13/20 on the Borg scale) 500-m treadmill-walking test. Age, weight, height, walk time, and heart rate during the 500-m test were entered into prediction equations previously validated for VO

resultsDirectly measured and estimated VO

conclusionsA moderate and self-regulated 500-m treadmill-walking test is a valid tool for VO

Indexed as

Cardiorespiratory FitnessExercise ToleranceOxygen ConsumptionStroke VolumeVentricular Function, LeftWalkingAdultAgedAged, 80 and overAge FactorsExercise TestHealth StatusHeart FailureHumansMaleMiddle AgedCardiorespiratory fitnessHeart failureLeft ventricular dysfunctionWalking test

Identifiers

PMID29661150
PMCPMC5902976

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.