Evidence map›Paper›PMID 29661135›Full record

Observational studyBMC geriatrics2018

The relative burden of community-acquired pneumonia hospitalizations in older adults: a retrospective observational study in the United States.

Joshua D Brown, James Harnett, Richard Chambers, Reiko Sato

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua D BrownDepartment of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, USA. joshua.brown@ufl.edu.ORCID 0000-0002-2973-1021
James HarnettGlobal Health and Value, Real World Data and Analytics, Pfizer Inc., New York, NY, USA.
Richard ChambersGlobal Product Development, Statistical Research Data Center, Pfizer, Inc., Collegeville, PA, USA.
Reiko SatoGlobal Health and Value, Outcomes and Evidence, Pfizer, Inc., Collegeville, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk of community-acquired pneumonia (CAP) increases with age and significantly impacts morbidity and mortality in the elderly population. The burden of illness and cost of preventing CAP has not been compared to other serious diseases.

methodsThis retrospective analysis used claims data from 2014 to 2015 and compared hospitalizations for CAP, myocardial infarction (MI), stroke, and osteoporotic fractures (OF) in adults aged ≥65 years enrolled in a Medicare Advantage insurance plan. Individuals who had not already been hospitalized for one of these conditions and did not have evidence of long-term care were included in the study. Hospitalizations for each condition were described by length of stay, readmissions, mortality, and total costs. Preventive measures included vaccinations for CAP and medications for MI, stroke, and OF.

resultsA total of 1,949,352 individuals were included in the cohort. In 2015, the rate of CAP-related hospitalizations was the highest at 846.7 per 100,000 person-years compared to 405 for MI, 278.9 for stroke, and 343.9 for OF. Vaccination costs for CAP were $40.2 million including $14.1 million for pneumococcal and $26.1 million for influenza vaccines. The cost of preventive medications for MI and stroke reached over $661 million and OF totaled $169 million.

conclusionsAlthough CAP has a higher burden of hospitalization and total costs than MI, stroke, and OF in the elderly population, prevention efforts were disproportionately smaller for CAP. Prioritization of CAP prevention is needed to substantially reduce the burden of CAP.

Indexed as

Health Care CostsAgedAged, 80 and overCommunity-Acquired InfectionsFemaleHospitalizationHumansLong-Term CareMaleMedicare Part CRetrospective StudiesUnited StatesBurden of illnessCommunity-acquired pneumoniaGeriatricsVaccinations

Identifiers

PMID29661135
PMCPMC5902892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.