ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2018
Selenium deficiency and pregnancy outcome in pregnant women with HIV in Lagos, Nigeria.
Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis.BMJ global health · 2021Pooled it
- A Multicountry Analysis of Maternal Selenium Status in Pregnancy and Lactation and Infant Birth Outcomes: Findings from the Women First Maternal Preconception Study.The Journal of nutrition · 2026Trial
- Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Trial
- Gestational Selenium Exposure and Neonatal Health Outcomes: A Systematic Review of Mortality, Morbidity, and Neurobehavioral Development.Journal of clinical medicine · 2026Review
- Thyroid Disorders and Serum Selenium Levels in a Southwestern Nigerian Population.International journal of endocrinology · 2025Article
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- Provision of Small-Quantity Lipid-Based Nutrient Supplements Increases Plasma Selenium Concentration in Pregnant Women in Malawi: A Secondary Outcome of a Randomized Controlled Trial.Current developments in nutrition · 2022Article
- Maternal selenium status plays a crucial role on clinical outcomes of pregnant women with COVID-19 infection.Journal of medical virology · 2021Article
- Selenium Biofortification: Roles, Mechanisms, Responses and Prospects.Molecules (Basel, Switzerland) · 2021Review
- Maternal Serum Concentrations of Selenium, Copper, and Zinc during Pregnancy Are Associated with Risk of Spontaneous Preterm Birth: A Case-Control Study from Malawi.Journal of pregnancy · 2020Article
- Selenium and at-risk pregnancy: challenges and controversies.Thyroid research · 2020Review
- Selenium⁻Fascinating Microelement, Properties and Sources in Food.Molecules (Basel, Switzerland) · 2019Review
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Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the prevalence of maternal selenium deficiency and its effects on pregnancy outcomes in pregnant women with HIV in Lagos, Nigeria.
methodsThe present descriptive cross-sectional study enrolled women aged 15-49 years with HIV who were at 14-26 weeks of a singleton pregnancy and were attending Lagos University Teaching Hospital, Lagos, Nigeria, between August 1, 2016, and April 30, 2017. Participants were selected by consecutive sampling and baseline data were collected through interviews. Venous blood samples were obtained to measure selenium concentrations, and associations between low maternal selenium concentrations (defined as <0.89 μmol/L) and pregnancy outcomes were examined using bivariate and multivariate analysis.
resultsThe final analysis included 113 patients; selenium deficiency was recorded in 23 (20.4%) patients. Women with selenium deficiency had an approximately eight-fold higher risk of preterm delivery (adjusted odds ratio 7.61, 95% confidence interval 4.37-18.89; P=0.031) and of delivering a term neonate with a low delivery weight (adjusted odds ratio 8.11, 95% confidence interval 3.27-17.22; P=0.012), compared with women with a normal selenium concentration.
conclusionThe prevalence of selenium deficiency among pregnant women with HIV in Lagos was relatively high. The significant associations observed between maternal selenium deficiency and adverse pregnancy outcomes could have implications for the future management of HIV in pregnancy.
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