Evidence map›Paper›PMID 29660815›Full record

ArticleTropical medicine & international health : TM & IH2018

Scaling down of a deworming programme among school-age children after a thirty-year successful intervention in the Bolivian Chaco.

Michele Spinicci, Fabio Macchioni, David Rojo, Herlan Gamboa, Ana Liz Villagrán, Yolanda Vallejos, Marianne Strohmeyer, Mimmo Roselli, Simona Gabrielli, Gabriella Cancrini and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The American journal of tropical medicine and hygiene · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 5 countries.

Michele SpinicciDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Florence, Italy.
Fabio MacchioniDipartimento di Scienze Veterinarie, Università degli Studi di Pisa, Pisa, Italy.
David RojoEscuela de Salud del Chaco Tekove Katu, Gutierrez, Bolivia.
Herlan GamboaFacultad Integral del Chaco, Universidad Autónoma Gabriel René Moreno, Camiri, Bolivia.
Ana Liz VillagránHospital Básico de Villa Montes, Villa Montes, Bolivia.
Yolanda VallejosHospital Municipal de Camiri, Camiri, Bolivia.
Marianne StrohmeyerDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Florence, Italy.
Mimmo RoselliDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Florence, Italy.
Simona GabrielliDipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Rome, Italy.
Gabriella CancriniDipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Rome, Italy.
Joaquín MonasterioServicio Departamental de Salud de Santa Cruz, Santa Cruz, Bolivia.
Paul CastellanosServicio Departamental de Salud de Tarija, Tarija, Bolivia.
Grover Adolfo ParedesPrograma Nacional de Zoonosis, Ministerio de Salud, La Paz, Bolivia.
Sdenka MauryUnidad de Epidemiologia, Ministerio de Salud, La Paz, Bolivia.
Adolfo ZárateUnidad de Epidemiologia, Ministerio de Salud, La Paz, Bolivia.
Rodolfo RocabadoServicios Generales de Salud, Ministerio de Salud, La Paz, Bolivia.
Piero OlliaroSpecial Programme for Research and Training in Tropical Diseases (TDR), WHO, Geneva, Switzerland.
Antonio MontresorDepartment of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland.
Alessandro BartoloniDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Florence, Italy.
Ministerio de Salud · BOUniversity of Florence · ITSapienza University of Rome · ITCâmara Municipal de Lisboa · PTDrugs for Neglected Diseases Initiative · CHGabriel René Moreno Autonomous University · BOHospital Montecelo · ESUniversidad Autónoma Juan Misael Saracho · BOUniversidad Nacional del Oriente · BOUniversidad Privada Del Chaco · BOUniversity of Pisa · ITWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivePreventive chemotherapy is the WHO-recommended control method for soil-transmitted helminthiases. In the Bolivian Chaco, 6-monthly single-dose mebendazole delivery to school-age children achieved a dramatic decrease in soil-transmitted helminthiases prevalence between 1987 and 2013. Consequently, in September 2016, preventive chemotherapy delivery was interrupted in nine rural communities. In compliance with WHO recommendations, we intensified surveillance to monitor soil-transmitted helminthiases prevalence and detect potential changes that would require interventions.

methodsWe conducted two cross-sectional parasitology surveys 12 months apart (September 2016-2017) among school-age children living in the communities where preventive chemotherapy delivery had been halted. Study design, methods of sampling and sample analysis technique (direct microscopy, Kato-Katz technique) followed WHO recommendations, aiming to obtain data representative of the Bolivian Chaco ecological zone.

resultsWe collected 426 samples in 2016 and 520 in 2017. Soil-transmitted helminthiasis prevalence was unremarkable: 0.7% (95% CI 0-1.5%) in 2016 and 0.8% (0-1.5%) in 2017. Conversely, the prevalence of tapeworms (13% in 2016, 12% in 2017) and intestinal protozoan infections (81% in 2016 and 75% in 2017) continued to be high.

conclusionsOur findings support the role of preventive chemotherapy in reducing soil-transmitted helminthiases transmission, as otherwise poor hygienic and health conditions persist in the Bolivian Chaco. A national survey, involving areas from all the ecological zones of Bolivia, is now warranted.

Indexed as

AnthelminticsBoliviaChemopreventionChildCross-Sectional StudiesFemaleHelminthiasisHumansMaleMebendazolePrevalenceProgram EvaluationRural PopulationSoilAnthelminticsMebendazoleSoilBoliviaBolivieenquêtehelminthiases transmises par le solprevalenceprévalenceprotozoonoseprotozoonosissoil-transmitted helminthiasessurveytapewormsténias

Identifiers

PMID29660815
PMCPMC5989933
OpenAlexW2800882226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.