ArticleAngewandte Chemie (International ed. in English)2018
CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes.
Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- General access to azoles through tailored nitrogen-nitrogen bond construction.Nature communications · 2026Article
- Diastereodivergent Hydroamidation of Methylenecyclohexanes With Differentiated Active Catalytic Species.Angewandte Chemie (International ed. in English) · 2026Article
- Transition-Metal Hydride Catalysis Meets Nitrenoid Transfer: Design Principles for Precision C-N Bond Formation.Accounts of chemical research · 2026Article
- Enantioconvergent Chan-Lam Coupling: Synthesis of Chiral Benzylic Amides via Cu-Catalyzed Deborylative Amidation.Journal of the American Chemical Society · 2025Article
- Continuous-Flow Synthesis of Primary Vinylarenes via Inline Grignard Reagent Formation and Peterson Olefination.ACS omega · 2025Article
- Dioxazolones as electrophilic amide sources in copper-catalyzed and -mediated transformations.Beilstein journal of organic chemistry · 2025Review
- Copper-catalyzed synthesis of primary amides through reductive N-O cleavage of dioxazolones.RSC advances · 2024Article
- Rhodium(III)-Catalyzed Remote Hydroamidation of Internal Alkenes via Chain Walking.ACS catalysis · 2023Article
- Rhodium(III)-Catalyzed Anti-Markovnikov Hydroamidation of Unactivated Alkenes Using Dioxazolones as Amidating Reagents.Journal of the American Chemical Society · 2022Article
- Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols.Nature communications · 2022Article
- Enantioselective synthesis of α-aminoboronates by NiH-catalysed asymmetric hydroamidation of alkenyl boronates.Nature communications · 2022Article
- An umpolung-enabled copper-catalysed regioselective hydroamination approach to α-amino acids.Chemical science · 2021Article
- Highly chemoselective synthesis of hindered amides via cobalt-catalyzed intermolecular oxidative hydroamidation.Nature communications · 2021Article
- Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles.Organic letters · 2021Article
- CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition.Accounts of chemical research · 2020Article
- Enantioselective Hydroamination of Alkenes with Sulfonamides Enabled by Proton-Coupled Electron Transfer.Journal of the American Chemical Society · 2020Article
- α-Branched amines by catalytic 1,1-addition of C-H bonds and aminating agents to terminal alkenes.Nature catalysis · 2019Article
- Cross-Coupling of Heteroatomic Electrophiles.Chemical reviews · 2019Review
- Preparation of Chiral Allenes through Pd-Catalyzed Intermolecular Hydroamination of Conjugated Enynes: Enantioselective Synthesis Enabled by Catalyst Design.Journal of the American Chemical Society · 2019Article
- A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination.Journal of the American Chemical Society · 2018Article
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Authors and funding
5 authors.
Funding
Abstract
A CuH-catalyzed enantioselective hydroamidation reaction of vinylarenes has been developed using readily accessible 1,4,2-dioxazol-5-ones as electrophilic amidating reagents. This method provides a straightforward and efficient approach to synthesize chiral amides in good yields with high levels of enantiopurity under mild conditions. Moreover, this transformation tolerates substrates bearing a broad range of functional groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.