Evidence map›Paper›PMID 29660244›Full record

ArticleDiabetes, obesity & metabolism2018

Unaccounted for regression to the mean renders conclusion of article titled "Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin" unsubstantiated.

Chanaka N Kahathuduwa, Diana M Thomas, Cynthia Siu, David B Allison

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, obesity & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Chanaka N KahathuduwaDepartment of Human Development and Family Studies, Texas Tech University, Lubbock, Texas.ORCID 0000-0003-2049-4901
Diana M ThomasDepartment of Mathematics, US Military Academy, West Point, New York.
Cynthia SiuCOS & Associates Ltd, Central, Hong Kong.
David B AllisonDepartment of Epidemiology and Biostatistics, School of Public Health - Bloomington, Indiana University, Bloomington, Indiana.

Funding

Strengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8M
The Mathematical Sciences in Obesity ResearchR25DK099080 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID B ALLISON, Andrew W Brown · 2013 to 2026
$1.2M
NHLBI NIH HHS R25 HL124208NIDDK NIH HHS R25 DK099080
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Glycated HemoglobinSodium-Glucose Transporter 2Benzhydryl CompoundsDiabetes Mellitus, Type 2GlucosidesHypoglycemic AgentsUric Acid6-((4-ethylphenyl)methyl)-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)spiro(isobenzofuran-1(3H),2'-(2H)pyran)-3',4',5'-triolBenzhydryl CompoundsGlucosidesGlycated HemoglobinHypoglycemic AgentsSodium-Glucose Transporter 2Uric Acid

Identifiers

PMID29660244
PMCPMC6043394

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.