ArticleGenome biology and evolution2018
The Genome Sequence of "Candidatus Fokinia solitaria": Insights on Reductive Evolution in Rickettsiales.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genomic evolution and adaptation of arthropod-associated Rickettsia.Scientific reports · 2022Pooled it
- The Nitroplast and Its Relatives Support a Universal Model of Features Predicting Gene Retention in Endosymbiont and Organelle Genomes.Genome biology and evolution · 2024Article
- Symbionts of Ciliates and Ciliates as Symbionts.Indian journal of microbiology · 2024Review
- Article
- Cellular interactions and evolutionary origins of endosymbiotic relationships with ciliates.The ISME journal · 2024Review
- Microbiomes of Blood-Feeding Triatomines in the Context of Their Predatory Relatives and the Environment.Microbiology spectrum · 2023Article
- The terrestrial isopod symbiont 'Candidatus Hepatincola porcellionum' is a potential nutrient scavenger related to Holosporales symbionts of protists.ISME communications · 2023Article
- Metagenome diversity illuminates origins of pathogen effectors.bioRxiv : the preprint server for biology · 2023Article
- Bacterial symbiosis in ciliates (Alveolata, Ciliophora): Roads traveled and those still to be taken.The Journal of eukaryotic microbiology · 2022Review
- The evolutionary origin of host association in the Rickettsiales.Nature microbiology · 2022Article
- Gene Transfer Agents in Bacterial Endosymbionts of Microbial Eukaryotes.Genome biology and evolution · 2022Article
- The "Other"Applied and environmental microbiology · 2022Review
- Identification of a NovelFrontiers in microbiology · 2021Article
- The Obligate Symbiont "Frontiers in microbiology · 2020Article
- Deianiraea, an extracellular bacterium associated with the ciliate Paramecium, suggests an alternative scenario for the evolution of Rickettsiales.The ISME journal · 2019Article
- The Hidden World of Rickettsiales Symbionts: "Candidatus Spectririckettsia obscura," a Novel Bacterium Found in Brazilian and Indian Paramecium caudatum.Microbial ecology · 2019Article
- SeqDeχ: A Sequence Deconvolution Tool for Genome Separation of Endosymbionts From Mixed Sequencing Samples.Frontiers in genetics · 2019Article
- Pandoravirus Celtis Illustrates the Microevolution Processes at Work in the GiantFrontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Candidatus Fokinia solitaria" is an obligate intracellular endosymbiont of a unicellular eukaryote, a ciliate of the genus Paramecium. Here, we present the genome sequence of this bacterium and subsequent analysis. Phylogenomic analysis confirmed the previously reported positioning of the symbiont within the "Candidatus Midichloriaceae" family (order Rickettsiales), as well as its high sequence divergence from other members of the family, indicative of fast sequence evolution. Consistently with this high evolutionary rate, a comparative genomic analysis revealed that the genome of this symbiont is the smallest of the Rickettsiales to date. The reduced genome does not present flagellar genes, nor the pathway for the biosynthesis of lipopolysaccharides (present in all the other so far sequenced members of the family "Candidatus Midichloriaceae") or genes for the Krebs cycle (present, although not always complete, in Rickettsiales). These results indicate an evolutionary trend toward a stronger dependence on the host, in comparison with other members of the family. Two alternative scenarios are compatible with our results; "Candidatus Fokinia solitaria" could be either a recently evolved, vertically transmitted mutualist, or a parasite with a high host-specificity.
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