ReviewAdvances in nutrition (Bethesda, Md.)2018
Nutritional Genomics and Direct-to-Consumer Genetic Testing: An Overview.
Review in Advances in nutrition (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does Personalized Nutrition Advice Improve Dietary Intake in Healthy Adults? A Systematic Review of Randomized Controlled Trials.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Article
- Personalized nutrition for healthy aging: precision diets based on genomic, metabolic, and microbiome profiles.Frontiers in nutrition · 2026Review
- Advancements in nutritional diagnosis and support strategies during the perioperative period for patients with liver cancer.World journal of gastrointestinal surgery · 2024Review
- Obesity and Nutrigenetics Testing: New Insights.Nutrients · 2024Review
- Cow's Milk: A Benefit for Human Health? Omics Tools and Precision Nutrition for Lactose Intolerance Management.Nutrients · 2024Review
- Current insights into genome-based personalized nutrition technology: a patent review.Frontiers in nutrition · 2024Review
- Components, prospects and challenges of personalized prevention.Frontiers in public health · 2023Review
- Demand for Direct-to-Consumer Genetic Testing Services in China and Its Implications for Precision Public Health - China, 2021.China CDC weekly · 2022Article
- A review of the Mediterranean diet and nutritional genomics in relation to cancer in women.Journal of preventive medicine and hygiene · 2022Review
- Review
- Interaction of obesity polygenic score with lifestyle risk factors in an electronic health record biobank.BMC medicine · 2022Article
- Genetic risk for obesity and the effectiveness of the ChooseWell 365 workplace intervention to prevent weight gain and improve dietary choices.The American journal of clinical nutrition · 2022Article
- New Opportunities to Advance the Field of Sports Nutrition.Frontiers in sports and active living · 2022Review
- Development of Personalized Nutrition: Applications in Lactose Intolerance Diagnosis and Management.Nutrients · 2021Review
- Review
- Review
- Direct-to-Consumer Nutrigenetics Testing: An Overview.Nutrients · 2020Review
- From nutrigenomics to personalizing diets: are we ready for precision medicine?The American journal of clinical nutrition · 2019Article
- Genetic determinants of beverage consumption: Implications for nutrition and health.Advances in food and nutrition research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing prevalence in polygenic diseases, such as obesity, cardiovascular disease, and type 2 diabetes, observed over the past few decades is more likely linked to a rapid transition in lifestyle rather than to changes in the sequence of the nuclear genome. In the new era of precision medicine, nutritional genomics holds the promise to be translated into tailored nutritional strategies to prevent and manage polygenic diseases more effectively. Nutritional genomics aims to prevent, treat, and manage polygenic diseases through targeted therapies formulated from individuals' genetic makeup and dietary intake. Direct-to-consumer genetic testing (DTC-GT) has become commercially available to equip individuals with information on their genetic vulnerability to different diseases. This information may potentially prompt behavioral changes against adverse factors. However, scientific evidence behind the clinical recommendations is a matter of continuous debate, and behavioral modifications after disclosing genetic information remain inconclusive. In this review, we provide an overview of nutritional genomics and related nutritional DTC-GT services and discuss whether available data are sufficient to be translated into clinical recommendations and public health initiatives. Overall, the scientific evidence supporting the dissemination of genomic information for nutrigenomic purposes remains sparse. Therefore, additional knowledge needs to be generated, particularly for polygenic traits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.