ArticlePlastic and reconstructive surgery2018
The Cost of Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer.
Article in Plastic and reconstructive surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05637216 (A Pilot Study of Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients), which is not on this map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study of Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients
Who cites it
12 citing papers in PubMed.
- Association Between Decision Regret and Psychosocial Outcomes Following Surgery Among Women with Unilateral Nonhereditary Breast Cancer.Annals of surgical oncology · 2026Article
- Patient Out-of-Pocket Costs and Healthcare Utilization Related to Mastectomy vs Breast Conservation: A Claims-Based Study.Journal of surgical oncology · 2026Article
- The Cost-Effectiveness and Cost Savings of Gender-Affirming Mastectomy.Transgender health · 2026Article
- Cumulative Medical Costs of Prepectoral Versus Subpectoral Implant-based Breast Reconstruction: A Single-Center Retrospective Analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Society of Surgical Oncology Breast Disease Site Working Group Statement on Contralateral Mastectomy: Indications, Outcomes, and Risks.Annals of surgical oncology · 2024Review
- Does a brief surgeon training in negotiation theory principles decrease rates of contralateral prophylactic mastectomy?Breast cancer research and treatment · 2023Article
- Nationwide Trends in Contralateral Prophylactic Mastectomies: An Analysis of 55,060 Unilateral Breast Cancer Patients.Plastic and reconstructive surgery. Global open · 2022Article
- Utilization of neoadjuvant chemotherapy in high-risk, node-negative early breast cancer.Cancer medicine · 2022Article
- Longitudinal Study of Psychosocial Outcomes Following Surgery in Women with Unilateral Nonhereditary Breast Cancer.Annals of surgical oncology · 2021Article
- Contralateral prophylactic mastectomy and implications for breast reconstruction.Gland surgery · 2021Review
- Article
- Discussion: The Cost of Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer.Plastic and reconstructive surgery · 2018Article
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7 authors.
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Abstract
backgroundContralateral prophylactic mastectomy may be unnecessary from an oncologic perspective; therefore, the debate persists about the value of contralateral prophylactic mastectomy in women with early-stage unilateral breast cancer. Given finite health care resources, this study aims to evaluate the cost of contralateral prophylactic mastectomy and breast reconstruction.
methodsWomen with unilateral breast cancer undergoing either unilateral mastectomy or unilateral mastectomy with contralateral prophylactic mastectomy and immediate breast reconstruction were selected from the Truven MarketScan databases between 2009 and 2013. Demographic and treatment data were recorded, and over an 18-month follow-up period, the treatment cost was tallied. A log-transformed linear model was used to compare cost between the groups.
resultsA total of 2343 women were identified who met our inclusion criteria, with 1295 undergoing unilateral mastectomy and 1048 undergoing contralateral prophylactic mastectomy. Complication rates within 18 months were similar for women undergoing unilateral mastectomy and contralateral prophylactic mastectomy (39 percent versus 42 percent; p = 0.17). Management with unilateral mastectomy with reconstruction required an adjusted cumulative mean cost of $33,557. Contralateral prophylactic mastectomy with reconstruction was an additional $11,872 in expenditure (p < 0.001). The cost of initial procedures (mean difference, $6467) and secondary procedures (mean difference, $2455) were the greatest contributors to cost.
conclusionsIn women with unilateral breast cancer, contralateral prophylactic mastectomy with reconstruction is more costly. The increased monetary cost of contralateral prophylactic mastectomy may be offset by improved quality of life. However, this financial reality is an important consideration when ongoing efforts toward reimbursement reform may not pay for contralateral prophylactic mastectomy if outcomes data are not presented to justify this procedure.
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