Evidence map›Paper›PMID 29659320›Full record

ArticleSubstance use & misuse2018

Opioid Discussion in the Twittersphere.

Rachel L Graves, Christopher Tufts, Zachary F Meisel, Dan Polsky, Lyle Ungar, Raina M Merchant

Abstract read
In one paragraph

Article in Substance use & misuse, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Curation and Extraction of Drug-Related Entities from Reddit Platform.Proceedings. IEEE International Conference on Healthcare Informatics · 2026
    Article
  5. Article
  6. Article
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  8. Article
  9. Can accurate demographic information about people who use prescription medications nonmedically be derived from Twitter?Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Opioid Misuse: A Review of the Main Issues, Challenges, and Strategies.International journal of environmental research and public health · 2022
    Review
  11. Article
  12. Methadone and suboxoneClinical toxicology (Philadelphia, Pa.) · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel L Gravesa Penn Medicine Center for Digital Health , University of Pennsylvania , Philadelphia , Pennsylvania , USA.ORCID 0000-0001-5253-044X
Christopher Tuftsa Penn Medicine Center for Digital Health , University of Pennsylvania , Philadelphia , Pennsylvania , USA.
Zachary F Meiselb Department of Emergency Medicine, Perelman School of Medicine , University of Pennsylvania , Philadelphia , Pennsylvania , USA.
Dan Polskyd Leonard Davis Institute of Health Economics , University of Pennsylvania , Philadelphia , Pennsylvania , USA.
Lyle Ungara Penn Medicine Center for Digital Health , University of Pennsylvania , Philadelphia , Pennsylvania , USA.
Raina M Merchanta Penn Medicine Center for Digital Health , University of Pennsylvania , Philadelphia , Pennsylvania , USA.

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Benjamin P. Linas · 2015 to 2026
$20.7M
NIDA NIH HHS P30 DA040500
6 · The paper itself

Abstract

backgroundThe rise in opioid use and overdose has increased the importance of improving data collection methods for the purpose of targeting resources to high-need populations and responding rapidly to emerging trends.

objectiveTo determine whether Twitter data could be used to identify geographic differences in opioid-related discussion and whether opioid topics were significantly correlated with opioid overdose death rate.

methodsWe filtered approximately 10 billion tweets for keywords related to opioids between July 2009 and October 2015. The content of the messages was summarized into 50 topics generated using Latent Dirchlet Allocation, a machine learning analytic tool. The correlation between topic distribution and census region, census division, and opioid overdose death rate were quantified.

resultsWe evaluated a tweet cohort of 84,023 tweets from 72,211 unique users across the US. Unique opioid-related topics were significantly correlated with different Census Bureau divisions and with opioid overdose death rates at the state and county level. Drug-related crime, language of use, and online drug purchasing emerged as themes in various Census Bureau divisions. Drug-related crime, opioid-related news, and pop culture themes were significantly correlated with county-level opioid overdose death rates, and online drug purchasing was significantly correlated with state-level opioid overdoses.

conclusionsRegional differences in opioid-related topics reflect geographic variation in the content of Twitter discussion about opioids. Analysis of Twitter data also produced topics significantly correlated with opioid overdose death rates. Ongoing analysis of Twitter data could provide a means of identifying emerging trends related to opioids.

Indexed as

Analgesics, OpioidCommunicationEpidemicsCohort StudiesCorrelation of DataCrimeCross-Sectional StudiesDrug OverdoseGeographyHumansOpioid-Related DisordersSocial MediaUnited StatesAnalgesics, OpioidCrimeopioidsoverdosesocial mediatwitter

Identifiers

PMID29659320
PMCPMC6314840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.