Evidence map›Paper›PMID 29658889›Full record

ArticlePhysics in medicine and biology2018

Cross-correlation analysis of pulse wave propagation in arteries: in vitro validation and in vivo feasibility.

Pierre Nauleau, Iason Apostolakis, Matthew McGarry, Elisa Konofagou

Abstract readValidation Study
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Improved Ultrasonic Local Pulse Wave Velocity Estimation Via Optimal Time Fiduciary Point Combination and Time Delays Fitness.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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  5. A physics-informed neural network approach for determining spatially varying arterial stiffness using ultrasound imaging: Finite Difference simulation and experimental plaque phantom validation.Proceedings of the ... IEEE International Symposium on Applications of Ferroelectrics. IEEE International Symposium on Applications of Ferroelectrics · 2024
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  10. Pulse Wave Imaging Coupled With Vector Flow Mapping: A Phantom, Simulation, and In Vivo Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pierre NauleauDepartment of Biomedical Engineering, Columbia University, New York, NY, United States of America.
Iason ApostolakisDepartment of Biomedical Engineering, Columbia University, New York, NY, United States of America.
Matthew McGarryDepartment of Biomedical Engineering, Columbia University, New York, NY, United States of America.
Elisa KonofagouDepartment of Biomedical Engineering, Columbia University, New York, NY, United States of America.

Funding

Carotid plaque assessment using Pulse Wave ImagingR01HL135734 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KONOFAGOU, ELISA E. · 2017 to 2020
$2.5M
NHLBI NIH HHS R01 HL135734
6 · The paper itself

Abstract

The stiffness of the arteries is known to be an indicator of the progression of various cardiovascular diseases. Clinically, the pulse wave velocity (PWV) is used as a surrogate for arterial stiffness. Pulse wave imaging (PWI) is a non-invasive, ultrasound-based imaging technique capable of mapping the motion of the vessel walls, allowing the local assessment of arterial properties. Conventionally, a distinctive feature of the displacement wave (e.g. the 50% upstroke) is tracked across the map to estimate the PWV. However, the presence of reflections, such as those generated at the carotid bifurcation, can bias the PWV estimation. In this paper, we propose a two-step cross-correlation based method to characterize arteries using the information available in the PWI spatio-temporal map. First, the area under the cross-correlation curve is proposed as an index for locating the regions of different properties. Second, a local peak of the cross-correlation function is tracked to obtain a less biased estimate of the PWV. Three series of experiments were conducted in phantoms to evaluate the capabilities of the proposed method compared with the conventional method. In the ideal case of a homogeneous phantom, the two methods performed similarly and correctly estimated the PWV. In the presence of reflections, the proposed method provided a more accurate estimate than conventional processing: e.g. for the soft phantom, biases of  -0.27 and -0.71 m · s

Indexed as

Phantoms, ImagingAdultArteriesFeasibility StudiesHumansImage Processing, Computer-AssistedIn Vitro TechniquesPulse Wave AnalysisSignal-To-Noise RatioUltrasonographyVascular StiffnessYoung Adult

Identifiers

PMID29658889
PMCPMC5975195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.