SynthesisCNS oncology2018
The role of ketogenic diets in the therapeutic management of adult and paediatric gliomas: a systematic review.
Synthesis in CNS oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of ketogenic metabolic therapy as an adjuvant to the current standard of care in the treatment of glioblastoma: A systematic review of clinical trials.Medical oncology (Northwood, London, England) · 2025Pooled it
- Pooled it
- Treatment options for progression or recurrence of glioblastoma: a network meta-analysis.The Cochrane database of systematic reviews · 2021Pooled it
- Ketogenic diets as an adjuvant therapy for glioblastoma (KEATING): a randomized, mixed methods, feasibility study.Journal of neuro-oncology · 2020Trial
- Metabolic Therapy in Glioblastoma-Mapping the Evidence for Ketogenic Diet as an Adjunctive Strategy.Nutrients · 2026Review
- Low Energy and Protein Intake in Brain Tumor Patients Despite Higher Adiposity: A Comparative Study with Gastrointestinal Cancer.Nutrients · 2026Article
- Review
- Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?Current nutrition reports · 2024Review
- Monitoring and Modulating Diet and Gut Microbes to Enhance Response and Reduce Toxicity to Cancer Treatment.Cancers · 2023Review
- Current knowledges in pharmaconutrition: "Frontiers in nutrition · 2023Review
- Insights into the Cellular Interactions and Molecular Mechanisms of Ketogenic Diet for Comprehensive Management of Epilepsy.Current neuropharmacology · 2022Review
- International Recommendations for the Management of Adults Treated With Ketogenic Diet Therapies.Neurology. Clinical practice · 2021Article
- Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks.Frontiers in nutrition · 2021Review
- Treatment of glioblastoma multiforme with "classic" 4:1 ketogenic diet total meal replacement.Cancer & metabolism · 2020Article
- The Role of Diet in Cancer Prevention and Chemotherapy Efficacy.Annual review of nutrition · 2020Review
- Ketogenic Diet for Malignant Gliomas: a Review.Current nutrition reports · 2020Review
- [Inhibitory effect of ketogenic diet on neuroblastoma in BALB/c-nu mouse models].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.Frontiers in neuroscience · 2020Article
- Author response to 'Problems associated with a highly artificial ketogenic diet: Letter to the Editor Re: van der Louw EJTM, Olieman JF, van den Bemt PMLA,Therapeutic advances in medical oncology · 2019Article
- Dietary Therapies: Emerging Paradigms in Therapy of Drug Resistant Epilepsy in Children : Based on 6th Dr. I. C. Verma Excellence in Research Award Oration.Indian journal of pediatrics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWe performed a systematic review of the evidence for effectiveness and acceptability of different ketogenic diets (KDs) in the therapeutic management of gliomas.
methodsThe search strategy included searches of seven electronic databases. Data extraction and quality assessment were undertaken independently by two authors.
resultsNo randomized clinical trials were identified. Six studies (n = 39) met the eligibility criteria for this review - all were case series or reports and therefore at high risk of bias. All studies reported overall or progression-free survival; however the effectiveness of KD interventions could not be established. Dietary acceptability was not reported.
conclusionThe effectiveness and acceptability of KDs in the management of gliomas is unknown and high quality randomized controlled trials are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.