ArticleJournal of the American Chemical Society2018
Asymmetric Synthesis of Gonytolide A: Strategic Use of an Aryl Halide Blocking Group for Oxidative Coupling.
Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Benzochromanone and Benzochromene Natural Products: Synthetic Strategies and Total Syntheses.Chemical record (New York, N.Y.) · 2026Review
- Recent advances in oxidative phenol coupling for the total synthesis of natural products.Natural product reports · 2024Review
- Article
- Asymmetric synthesis of chromanone lactonesChemical science · 2022Article
- New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems.Chemical reviews · 2020Article
- Synthetic Applications of Oxidative Aromatic Coupling-From Biphenols to Nanographenes.Angewandte Chemie (International ed. in English) · 2020Review
- Synthesis and Anticancer Activity of Structure Simplified Naturally-Inspired Dimeric Chromenone Derivatives.European journal of organic chemistry · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The first synthesis of the chromanone lactone dimer gonytolide A has been achieved employing vanadium(V)-mediated oxidative coupling of the monomer gonytolide C. An o-bromine blocking group strategy was employed to favor para- para coupling and to enable kinetic resolution of (±)-gonytolide C. Asymmetric conjugate reduction enabled practical kinetic resolution of a chiral, racemic precursor and the asymmetric synthesis of (+)-gonytolide A and its atropisomer.
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