Evidence map›Paper›PMID 29658183›Full record

ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2018

Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique.

Sepideh Kaviani, Dale A Schoeller, Eric Ravussin, Edward L Melanson, Sarah T Henes, Lara R Dugas, Ronald E Dechert, George Mitri, Paul F M Schoffelen, Pim Gubbels and 4 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  17. Energy expenditure due to gluconeogenesis in pathological conditions of insulin resistance.American journal of physiology. Endocrinology and metabolism · 2021
    Article
  18. Validity and reproducibility of VOScandinavian journal of medicine & science in sports · 2021
    Article
  19. Point-Counterpoint: Indirect Calorimetry Is Essential for Optimal Nutrition Therapy in the Intensive Care Unit.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sepideh KavianiDepartment of Foods and Nutrition, University of Georgia, Athens, Georgia, USA.
Dale A SchoellerDepartment of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, USA.
Eric RavussinPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Edward L MelansonDivision of Endocrinology, Metabolism, & Diabetes, University of Colorado Anschutz Medical Campus, Denver, Colorado, USA.
Sarah T HenesDepartment of Nutrition, Georgia State University, Atlanta, Georgia, USA.
Lara R DugasPublic Health Sciences, Loyola University, Chicago, Illinois, USA.
Ronald E DechertPediatric Respiratory Care, University of Michigan Health System, Ann Arbor, Michigan, USA.
George MitriPediatric Respiratory Care, University of Michigan Health System, Ann Arbor, Michigan, USA.
Paul F M SchoffelenDepartment of Human Biology & Movement Sciences, NUTRIM School for Nutrition, Toxicology & Metabolism, Maastricht University Medical Centre, Maastricht, the Netherlands.
Pim GubbelsTopsport Expertise & Innovation Centre, Sittard, the Netherlands.
Asa TornbergDepartment of Health Sciences, Lund University, Lund, Sweden.
Stephen GarlandDepartment of Health Sciences, Lund University, Lund, Sweden.
Marco AkkermansCenter of Expertise for Chronic Organ Failure, Horn, the Netherlands.
Jamie A CooperDepartment of Foods and Nutrition, University of Georgia, Athens, Georgia, USA.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Sujoy Ghosh · 2005 to 2026
$26.5M
TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
NCRR NIH HHS UL1 RR025780NIDDK NIH HHS P30 DK048520NIDDK NIH HHS P30 DK072476NIDDK NIH HHS T32 DK007665
6 · The paper itself

Abstract

backgroundSeveral indirect calorimetry (IC) instruments are commercially available, but comparative validity and reliability data are lacking. Existing data are limited by inconsistencies in protocols, subject characteristics, or single-instrument validation comparisons. The aim of this study was to compare accuracy and reliability of metabolic carts using methanol combustion as the cross-laboratory criterion.

methodsEight 20-minute methanol burn trials were completed on 12 metabolic carts. Respiratory exchange ratio (RER) and percent O

resultsFor accuracy, 1 Omnical, Cosmed Quark CPET (Cosmed), and both Parvos (Parvo Medics trueOne 2400) measured all 3 variables within 2% of the true value; both DeltaTracs and the Vmax Encore System (Vmax) showed similar accuracy in measuring 1 or 2, but not all, variables. For reliability, 8 instruments were shown to be reliable, with the 2 Omnicals ranking best (coefficient of variation [CV] < 1.26%). Both Cosmeds, Parvos, DeltaTracs, 1 Jaeger Oxycon Pro (Oxycon), Max-II Metabolic Systems (Max-II), and Vmax were reliable for at least 1 variable (CV ≤ 3%). For multiple regression, humidity and amount of combusted methanol were significant predictors of RER (R

conclusionsOmnical, Parvo, Cosmed, and DeltaTrac had greater accuracy and reliability. The small number of instruments tested and expected differences in gas calibration variability limits the generalizability of conclusions. Finally, humidity and temperature could be modified in the laboratory to optimize IC conditions.

Indexed as

Calorimetry, IndirectEuropeHot TemperatureHumansHumidityMaterials TestingMethanolOxidation-ReductionOxygen ConsumptionPulmonary Gas ExchangeRegression AnalysisReproducibility of ResultsSolventsUnited StatesMethanolSolventsaccuracyenergy metabolismindirect calorimetrymetabolic cartmethanolreliability

Identifiers

PMID29658183
PMCPMC6457648

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.