ArticleProgress in orthodontics2018
Effect of low level laser and low intensity pulsed ultrasound therapy on bone remodeling during orthodontic tooth movement in rats.
Article in Progress in orthodontics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Efficacy of low-intensity pulsed ultrasound in orthodontic tooth movement and orthodontically induced root resorption in animal and human studies: a systematic review and meta-analysis.Clinical oral investigations · 2024Pooled it
- Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st Week of Pain Perception in Four Treatment Modalities.Pain research & management · 2019Trial
- Review
- Biphasic energy dependent effects of 650 nm diode laser photobiomodulation on orthodontic tooth movement and compression zone bone remodeling in vivo.BMC oral health · 2026Article
- Evaluation of in Vivo Effects of Low-Intensity Pulsed Ultrasound and Low-Level Laser Therapy on Premaxillary Suture During Rapid Maxillary Expansion.Turkish journal of orthodontics · 2025Article
- The Impact of Therapeutic Ultrasound on Bone Radio Density Following Orthodontic Treatment with Clear Aligners: A Preliminary StudyCurrent medical imaging · 2025Article
- Age-related alveolar bone maladaptation in adult orthodontics: finding new ways out.International journal of oral science · 2024Review
- Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatmentWorld journal of stem cells · 2024Article
- Low-intensity pulsed ultrasound promotes the osteogenesis of mechanical force-treated periodontal ligament cells via Piezo1.Frontiers in bioengineering and biotechnology · 2024Article
- The Effects and Mechanisms of PBM Therapy in Accelerating Orthodontic Tooth Movement.Biomolecules · 2023Review
- Low-intensity pulsed ultrasound regulates osteoblast-osteoclast crosstalk via EphrinB2/EphB4 signaling for orthodontic alveolar bone remodeling.Frontiers in bioengineering and biotechnology · 2023Article
- Article
- Article
- Ectopic Eye Tooth Management: Photobiomodulation/Low-Level Laser Emission Role in Root Resorption after Fixed Orthodontic Treatment.Healthcare (Basel, Switzerland) · 2022Article
- Impact of photobiomodulation and low-intensity pulsed ultrasound adjunctive interventions on orthodontic treatment duration during clear aligner therapy.The Angle orthodontist · 2021Article
- Oral Health Impact Profile in Orthodontic Patients with Ectopic Canine: A Prospective Clinical Intervention of Four Treatment Modalities.Healthcare (Basel, Switzerland) · 2021Article
- lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells.Stem cells international · 2021Article
- Orthodontically Induced External Apical Root Resorption in Class II Malocclusion.Case reports in dentistry · 2021Article
- The Use of Technology in the Management of Orthodontic Treatment-Related Pain.Pain research & management · 2021Review
- Examination of the effect of combined use of Er:YAG laser irradiation and mechanical force loading on bone metabolism using primary human gingival fibroblasts.Lasers in medical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuality bone regeneration, which leads to the improvement of bone remodeling, is essential for orthodontic treatment. In order to improve bone regeneration and increase the amount of tooth movement, different techniques have been implemented. The object of this study is to compare the effects of low-level laser therapy (LLLT), low-intensity pulsed ultrasound (LIPUS), and their combination on bone remodeling during orthodontic tooth movement.
methodsEighty (80) male, 6-week-old Sprague Dawley rats were grouped in to four groups, the first group was irradiated with (940 nm) diode laser, second group with LIPUS, and third group with combination of both LLLT and LIPUS. A forth group used was a control group in an incomplete block split-mouth design. The LLLT and LIPUS were used to treat the area around the moving tooth once a day on days 0-7, then the experiment was ended in each experimental endpoint (1, 3, 7, 14, and 21 days). For amount of tooth movement, models were imaged and analyzed. Histological examination was performed after staining with (hematoxylin and eosin) and (alizarin red and Alcian Blue) stain. One step reverse transcription-polymerase chain reaction RT-PCR was also performed to elucidate the gene expression of RANK, RANKL, OPG, and RUNX-2.
resultsThe amount of tooth movement, the histological bone remodeling, and the RT-PCR were significantly greater in the treatment groups than that in the control group. Among the treatment groups, the combination group was the highest and the LIPUS group was the lowest.
conclusionThese findings suggest that LLLT and LIPUS can enhance the velocity of tooth movement and improve the quality of bone remodeling during orthodontic tooth movement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.