Evidence map›Paper›PMID 29657955›Full record

ArticleOpen forum infectious diseases2018

Challenges Across the HIV Care Continuum for Patients With HIV/TB Co-infection in Atlanta, GA [corrected].

Marcos C Schechter, Destani Bizune, Michelle Kagei, David P Holland, Carlos Del Rio, Aliya Yamin, Omar Mohamed, Alawode Oladele, Yun F Wang, Paulina A Rebolledo and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Marcos C SchechterDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Destani BizuneRollins School of Public Health, Emory University, Atlanta, Georgia.
Michelle KageiEmory University, Atlanta, Georgia.
David P HollandDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Carlos Del RioDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Aliya YaminCommunicable Disease Prevention Branch, Fulton County Health Board of Health, Atlanta, Georgia.
Omar MohamedCommunicable Disease Prevention Branch, Fulton County Health Board of Health, Atlanta, Georgia.
Alawode OladeleDeKalb County Board of Health, Decatur, Georgia.
Yun F WangDepartment of Pathology and Laboratory Medicine, School of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Paulina A RebolledoDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Susan M RayDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Russell R KempkerDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
Emory University · USDeKalb County Board of Health · USGrady Memorial Hospital · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Intra Cavitary Pharmacokinetics and Drug Resistance in Pulmonary TuberculosisK23AI103044 · NIAID · EMORY UNIVERSITY · PI KEMPKER, RUSSELL RYAN · 2013 to 2017
$910k
NCATS NIH HHS UL1 TR000454NIAID NIH HHS K23 AI103044
6 · The paper itself

Abstract

Background: Antiretroviral therapy (ART) for persons with HIV infection prevents tuberculosis (TB) disease. Additionally, sequential ART after initiation of TB treatment improves outcomes. We examined ART use, retention in care, and viral suppression (VS) before, during, and 3 years following TB treatment for an inner-city cohort in the United States. Methods: Retrospective cohort study among persons treated for culture-confirmed TB between 2008 and 2015 at an inner-city hospital. Results: Among 274 persons with culture-confirmed TB, 96 (35%) had HIV co-infection, including 23 (24%) new HIV diagnoses and 73 (76%) previous diagnoses. Among those with known HIV prior to TB, the median time of known HIV was 6 years, and only 10 (14%) were on ART at the time of TB diagnosis. The median CD4 at TB diagnosis was 87 cells/uL. Seventy-four (81%) patients received ART during treatment for TB, and 47 (52%) has VS at the end of TB treatment. Only 32% of patients had continuous VS 3 years after completing TB treatment. There were 3 TB recurrences and 3 deaths post-TB treatment; none of these patients had retention or VS after TB treatment. Conclusions: Among persons with active TB co-infected with HIV, we found that the majority had known HIV and were not on ART prior to TB diagnosis, and retention in care and VS post-TB treatment were very low. Strengthening the HIV care continuum is needed to improve HIV outcomes and further reduce rates of active TB/HIV co-infection in our and similar settings.

Indexed as

continuous retentionHIVtuberculosisviral suppression

Identifiers

PMID29657955
PMCPMC5890473
OpenAlexW2796320956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.