Evidence map›Paper›PMID 29657919›Full record

ArticleToxicology reports2017

Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordination-linked behaviour in male rats.

Adejoke Olukayode Obajuluwa, Ayodele Jacob Akinyemi, Olakunle Bamikole Afolabi, Khalid Adekoya, Joseph Olurotimi Sanya, Azeez Olakunle Ishola

Abstract read
In one paragraph

Article in Toxicology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Pilot Study of the Long-Term Effects of Radiofrequency Electromagnetic Radiation Exposure on the Mouse Brain.International journal of environmental research and public health · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adejoke Olukayode ObajuluwaBiological Sciences Department, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Ayodele Jacob AkinyemiBiochemistry Department, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Olakunle Bamikole AfolabiBiochemistry Department, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Khalid AdekoyaCell Biology and Genetics Department, Faculty of Sciences, University of Lagos, Lagos, Nigeria.
Joseph Olurotimi SanyaPhysiology Department, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Azeez Olakunle IsholaAnatomy Department, College of Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear. Hence, this study sought to investigate the effect of 2.5 Ghz band radio-frequency electromagnetic waves (RF-EMF) exposure on cerebral cortex acetylcholinesterase (AChE) activity and their mRNA expression level as well as locomotor function and anxiety-linked behaviour in male rats. Animals were divided into four groups namely; group 1 was control (without exposure), group 2-4 were exposed to 2.5 Ghz radiofrequency waves from an installed WI-FI device for a period of 4, 6 and 8 weeks respectively. The results revealed that WiFi exposure caused a significant increase in anxiety level and affect locomotor function. Furthermore, there was a significant decrease in AChE activity with a concomitant increase in AChE mRNA expression level in WiFi exposed rats when compared with control. In conclusions, these data showed that long term exposure to WiFi may lead to adverse effects such as neurodegenerative diseases as observed by a significant alteration on AChE gene expression and some neurobehavioral parameters associated with brain damage.

Indexed as

AcetylcholinesteraseElectromagnetic wavesGene expressionmRNARadiofrequency

Identifiers

PMID29657919
PMCPMC5897318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.