ArticleEuropean journal of rheumatology2018
Primary hyperparathyroidism and Gougerot disease.
Article in European journal of rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors at 1 institution in 1 country.
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Abstract
Primary hyperparathyroidism (PHPT) is a common endocrine disorder caused by the overactivation of the parathyroid glands due to the autonomous production of the parathyroid hormone (PTH). The resultant hypercalcemia leads to a myriad of symptoms. Here we report the case of a 54-year-old female with a previous diagnosis of Gougerot disease, in whom clinical (diffuse bone pain, asthenia polydipsia, and polyuria) and laboratory features (calcium level, 3.1 mmol/L; phosphate level, 0.55 mmol/L; alkaline phosphatase level, 70 U/L; and intact PTH level, 1028.9 pmol/L) prompted the diagnosis of PHPT caused by a parathyroid adenoma as confirmed by anatomopathology. After treatment with renal replacement therapy, intravenous fluids and zolendronic acid, and subtotal parathyroidectomy, the patient status improved, with normal laboratory tests. However, the fortuitous nature of the association between Gougerot disease and PHPT as well as the physiopathological links between these two diseases remain to be specified.
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