ArticleRoyal Society open science2018
Division rate, cell size and proteome allocation: impact on gene expression noise and implications for the dynamics of genetic circuits.
Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- The Constrained Disorder Principle: A Paradigm Shift for Accurate Interactome Mapping and Information Analysis in Complex Biological Systems.Bioengineering (Basel, Switzerland) · 2025Review
- Resource allocation to cell envelopes and the scaling of bacterial growth rate.Physical biology · 2025Article
- Cyclo-stationary distributions of mRNA and Protein counts for random cell division times.bioRxiv : the preprint server for biology · 2025Article
- Spatial and Temporal Variation of Precipitation Drives the Genome Size Variation inEcology and evolution · 2024Article
- Review
- Effective bet-hedging through growth rate dependent stability.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Concentration fluctuations in growing and dividing cells: Insights into the emergence of concentration homeostasis.PLoS computational biology · 2022Article
- Article
- Benchmarking imputation methods for network inference using a novel method of synthetic scRNA-seq data generation.BMC bioinformatics · 2022Article
- Regulation of Phagotrophy by Prey, Low Nutrients, and Low Light in the Mixotrophic Haptophyte Isochrysis galbana.Microbial ecology · 2021Article
- Review
- Threshold accumulation of a constitutive protein explainsProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Coordination of gene expression noise with cell size: analytical results for agent-based models of growing cell populations.Journal of the Royal Society, Interface · 2021Article
- Article
- A bacterial size law revealed by a coarse-grained model of cell physiology.PLoS computational biology · 2020Article
- Predictive biology: modelling, understanding and harnessing microbial complexity.Nature reviews. Microbiology · 2020Review
- Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics.Royal Society open science · 2020Article
- Models of protein production along the cell cycle: An investigation of possible sources of noise.PloS one · 2020Article
- Microfluidic time-lapse analysis and reevaluation of the Bacillus subtilis cell cycle.MicrobiologyOpen · 2019Article
- Intrinsic and extrinsic noise of gene expression in lineage trees.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The cell division rate, size and gene expression programmes change in response to external conditions. These global changes impact on average concentrations of biomolecule and their variability or noise. Gene expression is inherently stochastic, and noise levels of individual proteins depend on synthesis and degradation rates as well as on cell-cycle dynamics. We have modelled stochastic gene expression inside growing and dividing cells to study the effect of division rates on noise in mRNA and protein expression. We use assumptions and parameters relevant to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.