Evidence map›Paper›PMID 29657789›Full record

ArticleRoyal Society open science2018

Sensitive colorimetric assay using insulin G-quadruplex aptamer arrays on DNA nanotubes coupled with magnetic nanoparticles.

A Rafati, A Zarrabi, S Abediankenari, M Aarabi, P Gill

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

A RafatiDepartment of Biotechnology, Faculty of Advanced Science and Technology, University of Isfahan, Isfahan, Iran.
A ZarrabiDepartment of Biotechnology, Faculty of Advanced Science and Technology, University of Isfahan, Isfahan, Iran.ORCID 0000-0003-0391-1769
S AbediankenariNanomedicine Group, Immunogenetics Research Center, Mazandaran University of Medical Science, Sari, Iran.
M AarabiDiabetes Research Center, Mazandaran University of Medical Science, Sari, Iran.
P GillNanomedicine Group, Immunogenetics Research Center, Mazandaran University of Medical Science, Sari, Iran.ORCID 0000-0002-9020-4263
Isfahan University of Technology · IRMazandaran University of Medical Sciences · IRGolestan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Described here is a methodology for fabrication of a sensitive colorimetric nanoassay for measurement of insulin using G-quadruplex aptamer arrays on DNA nanotubes (DNTs) coupled with magnetic nanoparticles. The spectroscopic findings (e.g. visible spectra, velocity assay and limit of detection determination) indicated a highly sensitive performance of this new nanoassay in comparison to those results obtained from the insulin assay with non-arrayed aptamers. The clinical performance statistics (i.e. paired sample

Indexed as

G-quadruplex aptamerinsulin colorimetric assayMNP-coupled DNA nanotube

Identifiers

PMID29657789
PMCPMC5882713
OpenAlexW2789389657

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.