Evidence map›Paper›PMID 29657752›Full record

ArticleRoyal Society open science2018

Graphene foam as a biocompatible scaffold for culturing human neurons.

Giovanna M D'Abaco, Cristiana Mattei, Babak Nasr, Emma J Hudson, Abdullah J Alshawaf, Gursharan Chana, Ian P Everall, Bryony Nayagam, Mirella Dottori, Efstratios Skafidas

Abstract read
In one paragraph

Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Novel CDKL5 targets identified in human iPSC-derived neurons.Cellular and molecular life sciences : CMLS · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Graphene-Based Materials for Efficient Neurogenesis.Advances in experimental medicine and biology · 2022
    Article
  7. Application of Graphene in Tissue Engineering of the Nervous System.International journal of molecular sciences · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanna M D'AbacoDepartment of Biomedical Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.ORCID 0000-0001-5793-4072
Cristiana MatteiCentre for Neural Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.
Babak NasrCentre for Neural Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.
Emma J HudsonDepartment of Anatomy and Neuroscience, School of Biomedical Sciences, The University of Melbourne, Carlton, Victoria, Australia.
Abdullah J AlshawafCentre for Neural Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.
Gursharan ChanaCentre for Neural Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.
Ian P EverallDepartment of Psychiatry, Royal Melbourne Hospital, The University of Melbourne, Carlton, Victoria, Australia.
Bryony NayagamDepartment of Audiology and Speech Pathology, University of Melbourne and Bionics Institute Melbourne, Carlton, Victoria, Australia.ORCID 0000-0003-1069-6059
Mirella DottoriDepartment of Biomedical Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.
Efstratios SkafidasCentre for Neural Engineering, Melbourne School of Engineering, The University of Melbourne, Carlton, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we explore the use of electrically active graphene foam as a scaffold for the culture of human-derived neurons. Human embryonic stem cell (hESC)-derived cortical neurons fated as either glutamatergic or GABAergic neuronal phenotypes were cultured on graphene foam. We show that graphene foam is biocompatible for the culture of human neurons, capable of supporting cell viability and differentiation of hESC-derived cortical neurons. Based on the findings, we propose that graphene foam represents a suitable scaffold for engineering neuronal tissue and warrants further investigation as a model for understanding neuronal maturation, function and circuit formation.

Indexed as

biocompatibilitygraphene foamhuman cortical neuronshuman stem cells

Identifiers

PMID29657752
PMCPMC5882676

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.