Evidence map›Paper›PMID 29657606›Full record

ArticlePrzeglad gastroenterologiczny2018

Early biliary drainage is associated with favourable outcomes in critically-ill patients with acute cholangitis.

Mohammed Aboelsoud, Osama Siddique, Alexander Morales, Young Seol, Mazen Al-Qadi

Abstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. EarlyWorld journal of gastrointestinal endoscopy · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammed AboelsoudDepartment of Medicine, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, USA.
Osama SiddiqueDepartment of Medicine, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, USA.
Alexander MoralesDepartment of Medicine, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, USA.
Young SeolDepartment of Medicine, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, USA.
Mazen Al-QadiDepartment of Medicine, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute cholangitis (AC) is a clinical condition that requires prompt medical management with IV fluids, antibiotics, and biliary drainage (BD). The optimal timing for BD remains unclear.

aimTo investigate the effect of biliary drainage timing on clinical outcomes in AC. MATERIAL AND

methodsWe conducted a retrospective study of patients with AC admitted to the ICU using the Multiparameter Intelligent Monitoring in Intensive Care III (MIMIC-III) database. Emergency department to BD time, hospital death, length of stay (LOS), and severity scores were extracted from the database. We investigated the effect of BD timing on mortality rates, persistent organ failure, and LOS.

resultsA total of 177 patients were included; 50% were males; median age was 75 years, in-hospital mortality was 9.6%, mean time-to-ERCP was 32 h (range: 0.42-229.6) with 76% meeting the Tokyo Guidelines (TG13) criteria for severe cholangitis, and median Simplified Acute Physiology Score II (SAPS II) was 42 (IQR: 33-51). Using 24 h as a cut-off, patients who underwent BD ≤ 24 h had less persistent organ failure (OR = 0.49; 95% CI: 0.26-0.96,

conclusionsIn critically-ill patients with acute cholangitis, early biliary drainage ≤ 24 h is associated with less persistent organ failure and shorter length of stay but had no effect on patient survival.

Indexed as

acute cholangitisbiliary drainagecritically-illendoscopic retrograde cholangiopancreatographyTokyo Guidelines 2013

Identifiers

PMID29657606
PMCPMC5894448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.