ArticleReproductive medicine and biology2010
A study of the effect of an extremely low oxygen concentration on the development of human embryos in assisted reproductive technology.
Article in Reproductive medicine and biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Impacts of Oxygen Tension on Developmental Competence of Preimplantation Embryos.Biomolecules · 2026Review
- Hyaluronan-enriched transfer medium (HETM) can improve the implantation rate in morphologically poor euploid blastocyst transfer.Archives of gynecology and obstetrics · 2023Article
- Oxygen concentration affects de novo DNA methylation and transcription in in vitro cultured oocytes.Clinical epigenetics · 2021Article
- Using a mild stimulation protocol combined with clomiphene citrate and recombinant follicle-stimulating hormone to determine the optimal number of oocytes needed to achieve pregnancy and reduce the concerns of patients.Reproductive medicine and biology · 2013Article
- Comparison of Pregnancy Outcomes Between Fresh Embryo Transfer in a Natural IVF Cycle and IUI Cycle Among Infertile Young Women.Journal of reproduction & infertilityArticle
- The Effect of a Newly Designed Needle on the Pain and Bleeding of Patients During Oocyte Retrieval of a Single Follicle.Journal of reproduction & infertilityArticle
- Limited Effects of Ultra-low Oxygen Concentration during Extended Embryo Culture onJournal of human reproductive sciencesArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To determine whether embryos cultured with a low oxygen level (2%) brought about beneficial effects on the outcome of ART. Methods: This is a sequential case-control embryo-culture study. Embryos were cultured either with a gas mixture containing 2% O Results: The cleavage rate in the low-oxygen group (94.4%) was similar to that (94.7%) in the conventional group. The mean number of blastomeres on Day 3 in the low-oxygen group (mean ± SE) was 6.5 ± 1.9, and this was significantly lower than in the conventional group (6.8 ± 1.9, Conclusions: Overall, culture of embryos at the low oxygen level did not significantly improve ART results compared with embryos grown in 5% oxygen. The study suggests that a low oxygen level worsens embryo morphology but does not impair embryo viability.
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Registered trials
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