Evidence map›Paper›PMID 29657488›Full record

ArticleJournal of forensic dental sciences

Sex determination from mesiodens of Indian children by amelogenin gene.

Mohit Srivastava, Swati Tripathi, Madhusudan Astekar, Deepa Singal, Aditi Srivastava, Pallavi Vashisth

Abstract read
In one paragraph

Article in Journal of forensic dental sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mohit SrivastavaDepartment of Pedodontics and Preventive Dentistry, Karnavathi School of Dentistry, Gandhinagar, Gujarat, India.
Swati TripathiDepartment of Pedodontics and Preventive Dentistry, Institute of Dental Sciences, Mahatma Jyotiba Phule Rohilkhand University, Bareilly, Uttar Pradesh, India.
Madhusudan AstekarDepartment of Oral and Maxillofacial Pathology, Institute of Dental Sciences, Mahatma Jyotiba Phule Rohilkhand University, Bareilly, Uttar Pradesh, India.
Deepa SingalSingla Dental and Eye Care Center, Moga, Punjab, India.
Aditi SrivastavaDepartment of Pedodontics and Preventive Dentistry, Karnavathi School of Dentistry, Gandhinagar, Gujarat, India.
Pallavi VashisthDepartment of Pedodontics and Preventive Dentistry, Institute of Dental Sciences, Mahatma Jyotiba Phule Rohilkhand University, Bareilly, Uttar Pradesh, India.
M.J.P. Rohilkhand University · INKadi Sarva Vishwavidyalaya · INVasan Eye Care Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe identification of sex is the first and the foremost step in forensic science. Teeth consist of enamel which is the hardest tissue available in the body, protector of DNA presents in pulp tissue at the time of exposure of tooth to adverse conditions. Teeth can be stated as a sealed box of mystery as it contains various human and bacterial DNA for molecular utilization. AIM AND

objectiveThe aim is to determine sex from mesiodens on the basis of gene identification by the polymerase chain reaction (PCR). SETTINGS AND

designTotal number of sample was 8 human-extracted mesiodens. DNA was isolated and was subjected to PCR analysis with use of predesigned primers for amelogenin (AMEL) X and AMEL Y genes.

resultsIsolation of genomic and mitochondrial DNA from mesiodens was successful in six samples (75%). In samples, quantity of DNA present was also calculated.

conclusionMesiodens are a good source of DNA and are a very useful tool in identification of sex using PCR analysis which was simple and effective. Hence, the procedure presented in the present study can be applied for extraction of DNA and identification of sex for forensic purpose.

Indexed as

Amelogenin genemesiodenspolymerase chain reaction analysissex determination

Identifiers

PMID29657488
PMCPMC5887634
OpenAlexW2889896819

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.