Evidence map›Paper›PMID 29657484›Full record

ArticleJournal of proteomics & bioinformatics2010

Mining Unique-

Kai Ye, Zhenyu Jia, Yipeng Wang, Paul Flicek, Rolf Apweiler

Abstract read
In one paragraph

Article in Journal of proteomics & bioinformatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai YeMolecular Epidemiology section, Medical Statistics and Bioinformatics, Leiden University Medical Center, The Netherlands.
Zhenyu JiaDepartment of Pathology & Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Yipeng WangDepartment of Pathology & Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Paul FlicekEMBL Outstation, European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Rolf ApweilerEMBL Outstation, European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

Funding

Wellcome Trust 062023
6 · The paper itself

Abstract

Unique substrings in genomes may indicate high level of specificity which is crucial and fundamental to many genetics studies, such as PCR, microarray hybridization, Southern and Northern blotting, RNA interference (RNAi), and genome (re)sequencing. However, being unique sequence in the genome alone is not adequate to guaranty high specificity. For example, nucleotides mismatches within a certain tolerance may impair specificity even if an interested substring occur only once in the genome. In this study we propose the concept of unique-

Indexed as

Data miningGenomesMismatchSequence

Identifiers

PMID29657484
PMCPMC5894807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.