Evidence map›Paper›PMID 29657295›Full record

ArticleNon-coding RNA2017

Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma.

Dhruvitkumar S Sutaria, Jinmai Jiang, Ana Clara P Azevedo-Pouly, Eun Joo Lee, Megan R Lerner, Daniel J Brackett, Jo Vandesompele, Pieter Mestdagh, Thomas D Schmittgen

Open access · goldAbstract read
In one paragraph

Article in Non-coding RNA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Systemic Sclerosis Association with Malignancy.Clinical reviews in allergy & immunology · 2022
    Review
  5. Novel role of long non-coding RNAs in autoimmune cutaneous disease.Journal of cell communication and signaling · 2022
    Review
  6. Article
  7. DNA and RNA Binding Proteins: From Motifs to Roles in Cancer.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. IdentifyingPeerJ · 2020
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Dhruvitkumar S SutariaDepartment of Pharmaceutics, College of Pharmacy, University of Florida Gainesville, 32608 Florida, USA. dsutaria@ufl.edu.ORCID 0000-0001-8149-3481
Jinmai JiangDepartment of Pharmaceutics, College of Pharmacy, University of Florida Gainesville, 32608 Florida, USA. JJiang@cop.ufl.edu.
Ana Clara P Azevedo-PoulyDepartment of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, Ohio State University Columbus, 43210 Ohio, USA. ana.azevedo-pouly@utah.edu.
Eun Joo LeeCollege of Pharmacy and Wonkwang Oriental Medicines Research Institute, Wonkwang University, 54538 Iksan, Korea. eundoo@gmail.com.
Megan R LernerDepartment of Surgery, University of Oklahoma Heath Science Center, 73104 Oklahoma, USA. Megan-Lerner@ouhsc.edu.
Daniel J BrackettDepartment of Surgery, University of Oklahoma Heath Science Center, 73104 Oklahoma, USA. Daniel-Brackett@ouhsc.edu.
Jo VandesompeleCenter for Medical Genetics, Ghent University Hospital, 9000 Ghent, Belgium. joke.vandesompele@ugent.be.ORCID 0000-0001-6274-0184
Pieter MestdaghCenter for Medical Genetics, Ghent University Hospital, 9000 Ghent, Belgium. Pieter.Mestdagh@UGent.be.
Thomas D SchmittgenDepartment of Pharmaceutics, College of Pharmacy, University of Florida Gainesville, 32608 Florida, USA. tschmittgen@ufl.edu.
University of Florida · USGhent University Hospital · BEUniversity of Oklahoma Health Sciences Center · USThe Ohio State University · USWonkwang University · KR

Funding

Early Diagnosis of Pancreatic CancerU01CA111294 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BATRA, SURINDER K., HOLLINGSWORTH, MICHAEL A. · 2004 to 2015
$7.1M
NCI NIH HHS U01 CA111294
6 · The paper itself

Abstract

A gene array was used to profile the expression of 22,875 long non-coding RNAs (lncRNAs) and a large number of protein coding genes in 47 specimens of pancreatic ductal adenocarcinoma (PDAC), adjacent benign pancreas and the pancreas from patients without pancreatic disease. Of the lncRNAs profiled, the expression of 126 were significantly increased and 260 were decreased in the tumors (

Indexed as

HNRNPUHNRNPU processed transcriptLNATM gapmerslncRNAncRNA00201pancreatic cancer

Identifiers

PMID29657295
PMCPMC5831917
OpenAlexW2749287856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.