Evidence map›Paper›PMID 29656950›Full record

ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2018

The Elicitation of Relaxation and Interoceptive Awareness Using Floatation Therapy in Individuals With High Anxiety Sensitivity.

Justin S Feinstein, Sahib S Khalsa, Hung Yeh, Obada Al Zoubi, Armen C Arevian, Colleen Wohlrab, Marie K Pantino, Laci J Cartmell, W Kyle Simmons, Murray B Stein and 1 more

4 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04368689 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

The Feasibility and Examination of the Effects of Floatation-based Reduced Environmental Stimulation Therapy (REST) on a Community Sample With Posttraumatic Stress Disorder (PTSD)

TypeinterventionalSponsorMedical College of WisconsinRan2021 to 2027Enrolled30ConditionsPost-Traumatic Stress DisordersArmsFloatation-based reduced environmental stimulation therapy
NCT05977894 enrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Wellbeing Monitoring During Sequential Reduced Environmental Stimulation-Floatation

TypeobservationalSponsorMercy Health OhioRan2023 to 2026Enrolled50ConditionsBurnout, Professional, Negative Affect, Positive Affect, WellbeingArmsReduced Environmental Stimulation Therapy
NCT06332963 narecruitingnot on this mapstarted 2024, after this paper: background citation

Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa

TypeinterventionalSponsorLaureate Institute for Brain Research, Inc.Ran2024 to 2028Enrolled102ConditionsAnorexia Nervosa, Body Image Disturbance, InteroceptionArmsFloatation-REST, IFT, EFT
NCT07429617 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Darkness Retreat on Worry and Rumination in a Non-clinical Population: a Pilot Study

TypeinterventionalSponsorUniversity of Social Sciences and Humanities, WarsawRan2025 to 2026Enrolled30ConditionsStudy Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical RuminationArmsDarkness Retreat - Several Days of Seclusion in Complete Darkness
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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  14. Sensing the Self: The Role of the Insula and Interoception in Body Image.Current topics in behavioral neurosciences · 2025
    Review
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  20. Interoception in Fear Learning and Posttraumatic Stress Disorder.Focus (American Psychiatric Publishing) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Justin S FeinsteinLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma; Oxley College of Health Sciences, University of Tulsa, Tulsa, Oklahoma. Electronic address: feinstein.float@gmail.com.
Sahib S KhalsaLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma; Oxley College of Health Sciences, University of Tulsa, Tulsa, Oklahoma.
Hung YehLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma.
Obada Al ZoubiLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma; Gallogly College of Engineering, University of Oklahoma, Tulsa, Oklahoma.
Armen C ArevianDepartment of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California.
Colleen WohlrabLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma.
Marie K PantinoLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma.
Laci J CartmellOxley College of Health Sciences, University of Tulsa, Tulsa, Oklahoma.
W Kyle SimmonsLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma; Oxley College of Health Sciences, University of Tulsa, Tulsa, Oklahoma.
Murray B SteinDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Martin P PaulusLaureate Institute for Brain Research, University of Tulsa, Tulsa, Oklahoma.
Laureate Institute for Brain Research · USUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of Tulsa · US

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI Maëlle Camille Marie Gueguen · 2017 to 2026
$23.7M
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia NervosaK23MH112949 · NIMH · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI KHALSA, SAHIB · 2017 to 2021
$994k
NIGMS NIH HHS P20 GM121312NIMH NIH HHS K23 MH112949
6 · The paper itself

Abstract

backgroundFloatation-REST (Reduced Environmental Stimulation Therapy), an intervention that attenuates exteroceptive sensory input to the nervous system, has recently been found to reduce state anxiety across a diverse clinical sample with high levels of anxiety sensitivity (AS). To further examine this anxiolytic effect, the present study investigated the affective and physiological changes induced by Floatation-REST and assessed whether individuals with high AS experienced any alterations in their awareness for interoceptive sensation while immersed in an environment lacking exteroceptive sensation.

methodsUsing a within-subject crossover design, 31 participants with high AS were randomly assigned to undergo a 90-minute session of Floatation-REST or an exteroceptive comparison condition. Measures of self-reported affect and interoceptive awareness were collected before and after each session, and blood pressure was measured during each session.

resultsRelative to the comparison condition, Floatation-REST generated a significant anxiolytic effect characterized by reductions in state anxiety and muscle tension and increases in feelings of relaxation and serenity (p < .001 for all variables). Significant blood pressure reductions were evident throughout the float session and reached the lowest point during the diastole phase (average reduction >12 mm Hg). The float environment also significantly enhanced awareness and attention for cardiorespiratory sensations.

conclusionsFloatation-REST induced a state of relaxation and heightened interoceptive awareness in a clinical sample with high AS. The paradoxical nature of the anxiolytic effect in this sample is discussed in relation to Wolpe's theory of reciprocal inhibition and the regulation of distress via sustained attention to present moment visceral sensations such as the breath.

Indexed as

AdultAnti-Anxiety AgentsAnxietyAnxiety DisordersAttentionAwarenessEmotionsFemaleHumansInteroceptionMaleMiddle AgedSelf ConceptSensationYoung AdultAnti-Anxiety AgentsAnxietyBlood pressureFloatation-RESTFloatingInteroceptionMindfulnessNovel interventionRelaxation response

Identifiers

PMID29656950
PMCPMC6040829
OpenAlexW2791710617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.