ArticleMicrobial biotechnology2018
Efficacy of 7-benzyloxyindole and other halogenated indoles to inhibit Candida albicans biofilm and hyphal formation.
Article in Microbial biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 45 citations in OpenAlex.
- Antifungal and Antivirulence Activity of Alizarin againstACS infectious diseases · 2026Article
- Roles of Indole and Its Derivative in ModulatingInternational journal of molecular sciences · 2026Article
- Pogostone disrupts key virulence traits of Candida albicans: hyphal inhibition and biofilm suppression.BMC microbiology · 2026Article
- Diet, mycobiome and virome: from mucosal immunity to gut-brain axis regulation.Frontiers in nutrition · 2026Review
- Antifungal Activities of Multi-Halogenated Indoles Against Drug-ResistantInternational journal of molecular sciences · 2025Article
- Combating polymicrobial biofilm: recent approaches.Folia microbiologica · 2023Review
- 3,3'-Diindolylmethane (DIM): A Potential Therapeutic Agent against CariogenicAntibiotics (Basel, Switzerland) · 2023Article
- Synthesis of Bio-Based Polybenzoxazine and Its Antibiofilm and Anticorrosive Activities.Materials (Basel, Switzerland) · 2023Article
- Hydroquinones Including Tetrachlorohydroquinone Inhibit Candida albicans Biofilm Formation by Repressing Hyphae-Related Genes.Microbiology spectrum · 2022Article
- Halogenated Indoles Decrease the Virulence of Vibrio campbellii in a Gnotobiotic Brine Shrimp Model.Microbiology spectrum · 2022Article
- The Cell-Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii.Microbiology spectrum · 2022Article
- Grafted Chitosan-Hyaluronic Acid (CS-g-poly (MA-co-AN) HA) Complex Inhibits Fluconazole-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans.Microbiology spectrum · 2022Article
- Investigation of indole biodegradation by Cupriavidus sp. strain IDO with emphases on downstream biotransformation and indigo production.Environmental science and pollution research international · 2022Article
- Silicone Foley catheters impregnated with microbial indole derivatives inhibit crystalline biofilm formation byFrontiers in cellular and infection microbiology · 2022Article
- Antibiofilm and Antimicrobial Activities of Chloroindoles Against UropathogenicFrontiers in microbiology · 2022Article
- The In Vitro Potential of 1-(1Microorganisms · 2021Article
- Intestinal Infection ofFrontiers in microbiology · 2021Review
- Review
- Rapid Killing and Biofilm Inhibition of Multidrug-ResistantBiomolecules · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Certain pathogenic bacteria and yeast form biofilms on biotic and abiotic surfaces including medical devices and implants. Hence, the development of antibiofilm coating materials becomes relevant. The virulence of those colonizing pathogens can be reduced by inhibiting biofilm formation rather than killing pathogens using excessive amounts of antimicrobials, which is touted as one of the main reasons for the development of drug resistance. Candida albicans is an opportunistic fungal pathogen, and the transition of yeast cells to hyphal cells is believed to be a crucial virulence factor. Previous studies have shown that indole and its derivatives possess antivirulence properties against various bacterial pathogens. In this study, we used various indole derivatives to investigate biofilm-inhibiting activity against C. albicans. Our study revealed that 7-benzyloxyindole, 4-fluoroindole and 5-iodoindole effectively inhibited biofilm formation compared to the antifungal agent fluconazole. Particularly, 7-benzyloxyindole at 0.02 mM (4.5 μg ml
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.