Evidence map›Paper›PMID 29656466›Full record

ArticleInternational journal of experimental pathology2018

Evaluation of high-fat high-fructose diet treatment in factor VIII (coagulation factor)-deficient mouse model.

Alaknanda Mishra, Shailendra Arindkar, Preeti Sahay, Jerald Mahesh Kumar, Pramod K Upadhyay, Subeer S Majumdar, Perumal Nagarajan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Guideline
  2. Exploring the Complex Role of Coagulation Factor VIII in Chronic Liver Disease.Cellular and molecular gastroenterology and hepatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alaknanda MishraNational Institute of Immunology, New Delhi, India.
Shailendra ArindkarNational Institute of Immunology, New Delhi, India.
Preeti SahayNational Institute of Immunology, New Delhi, India.
Jerald Mahesh KumarCSIR-CCMB, Hyderabad, India.
Pramod K UpadhyayNational Institute of Immunology, New Delhi, India.
Subeer S MajumdarNational Institute of Immunology, New Delhi, India.
Perumal NagarajanNational Institute of Immunology, New Delhi, India.ORCID 0000-0003-4557-4633
National Institute of Immunology · INCentre for Cellular and Molecular Biology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD)-like conditions enhance the production and action of clotting factors in humans. However, studies examining the effect of NAFLD due to high-fat high-fructose (HFHF) diet in factor VIII-deficient (haemophilia A) animals or patients have not been reported previously. In this study, we investigated the individual role of factor VIII in the progression of diet-induced NAFLD in the factor 8

Indexed as

AnimalsCollagenDietary SugarsDiet, High-FatDisease Models, AnimalFactor VIIIFatty AcidsFructoseGenetic Predisposition to DiseaseHemophilia AInflammation MediatorsLipid DropletsLiverMaleMice, KnockoutMyeloid CellsCollagenDietary SugarsFactor VIIIFatty AcidsFructoseInflammation MediatorsTriglyceridesfactor 8−/−haemophilia Ahigh-fat high-fructosemetabolismnon-alcoholic fatty liver disease

Identifiers

PMID29656466
PMCPMC5917390
OpenAlexW2799760585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.