ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2018
Mediterranean diet and hip fracture incidence among older adults: the CHANCES project.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
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- The Impact of Physical Education Attendance and Diet on Bone Mineralization in Adolescents.Nutrients · 2025Article
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- Addressing osteoblast senescence: Molecular pathways and the frontier of anti-ageing treatments.Clinical and translational medicine · 2025Review
- Association between long-term exercise with different osteogenic index, dietary patterns, body composition, biological factors, and bone mineral density in female elite masters athletes.Scientific reports · 2025Article
- Are Dietary Patterns Relevant for Reducing the Risk of Fractures and Sarcopenia?Current osteoporosis reports · 2025Review
- Insights into Osteogenesis Induced by CrudeNutrients · 2024Article
- Review
- Review
- Plant-Based Diets and Risk of Hip Fracture in Postmenopausal Women.JAMA network open · 2024Article
- Nutritional strategies to optimise musculoskeletal health for fall and fracture prevention: Looking beyond calcium, vitamin D and protein.Bone reports · 2023Review
- Association of Alternative Dietary Patterns with Osteoporosis and Fracture Risk in Older People: A Scoping Review.Nutrients · 2023Article
- An investigation of the effect of acrylamide on fracture healing in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- The Impact of Diet on Bone and Fracture Risk in Diabetes.Current osteoporosis reports · 2022Review
- Glucoraphanin Increases Intracellular Hydrogen Sulfide (HNutrients · 2022Article
- Dietary organosulfur compounds: Emerging players in the regulation of bone homeostasis by plant-derived molecules.Frontiers in endocrinology · 2022Review
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 5 countries.
Funding
Abstract
The association between adherence to Mediterranean diet (MD) and hip fracture incidence is not yet established. In a diverse population of elderly, increased adherence to MD was associated with lower hip fracture incidence. Except preventing major chronic diseases, adhering to MD might have additional benefits in lowering hip fracture risk.
introductionHip fractures constitute a major public health problem among older adults. Latest evidence links adherence to Mediterranean diet (MD) with reduced hip fracture risk, but still more research is needed to elucidate this relationship. The potential association of adherence to MD with hip fracture incidence was explored among older adults.
methodsA total of 140,775 adults (116,176 women, 24,599 men) 60 years and older, from five cohorts from Europe and the USA, were followed-up for 1,896,219 person-years experiencing 5454 hip fractures. Diet was assessed at baseline by validated, cohort-specific, food-frequency questionnaires, and hip fractures were ascertained through patient registers or telephone interviews/questionnaires. Adherence to MD was evaluated by a scoring system on a 10-point scale modified to be applied also to non-Mediterranean populations. In order to evaluate the association between MD and hip fracture incidence, cohort-specific hazard ratios (HR), adjusted for potential confounders, were estimated using Cox proportional-hazards regression and pooled estimates were subsequently derived implementing random-effects meta-analysis.
resultsA two-point increase in the score was associated with a significant 4% decrease in hip fracture risk (pooled adjusted HR 0.96; 95% confidence interval (95% CI) 0.92-0.99, p
conclusionsIn this large sample of older adults from Europe and the USA, increased adherence to MD was associated with lower hip fracture incidence.
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Registered trials
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