Evidence map›Paper›PMID 29654881›Full record

SynthesisNeuropsychologia2018

A systematic literature review of sex differences in childhood language and brain development.

Andrew Etchell, Aditi Adhikari, Lauren S Weinberg, Ai Leen Choo, Emily O Garnett, Ho Ming Chow, Soo-Eun Chang

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuropsychologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 5 pooled it
21.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 5 syntheses or guidelines pooled it, 197 citations in OpenAlex.

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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Andrew EtchellDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA. Electronic address: aetchell@med.umich.edu.
Aditi AdhikariCollege of Arts and Sciences, University of North Carolina at Chapel Hill, USA.
Lauren S WeinbergCollege of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI, USA.
Ai Leen ChooDepartment of Communication Sciences and Disorders, Georgia State University, USA.
Emily O GarnettDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Ho Ming ChowDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA; Katzin Diagnostic & Research PET/MR Center, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA.
Soo-Eun ChangDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · USAlfred I. duPont Hospital for Children · USGeorgia State University · USUniversity of North Carolina at Chapel Hill · US

Funding

Sexual dimorphism of neural development underlying childhood stutteringR01DC011277 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Soo-Eun Chang · 2010 to 2026
$8.2M
Imaging genetics study of twins who stutterR21DC015312 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHANG, SOO-EUN · 2017 to 2018
$440k
NIDCD NIH HHS R01 DC011277NIDCD NIH HHS R21 DC015312
6 · The paper itself

Abstract

The extent of sex differences in childhood language development is unclear. We conducted a systematic literature review synthesizing results from studies examining sex differences in brain structure and function relevant to language development during childhood. We searched PubMed and Scopus databases, and this returned a total of 46 published studies meeting criteria for inclusion that directly examined sex differences in brain development relevant to language function in children. The results indicate that: (a) sex differences in brain structure or function do not necessarily lead to differences in language task performance; (b) evidence for sex differences in brain and language development are limited; (c) when present, sex differences often interact with a variety of factors such as age and task. Overall, the magnitude of sexual dimorphism of brain developmental trajectories associated with language is not as significant as previously thought. Sex differences were found, however, in studies employing tighter age ranges. This suggests that sex differences may be more prominent during certain developmental stages but are negligible in other stages, likely due to different rates of maturation between the sexes. More research is needed to improve our understanding of how sex differences may arise due to the influence of sex hormones and developmental stages, and how these differences may lead to differences in various language task performance. These studies are expected to provide normative information that may be used in studies examining neurodevelopmental disorders that frequently affect more males than females, and also often affect language development.

Indexed as

Child LanguageSex CharacteristicsBrainChildElectroencephalographyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleBrainChildrenDevelopmentLanguageLateralitySex differences

Identifiers

PMID29654881
PMCPMC5988993
OpenAlexW2797841254

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.