Evidence map›Paper›PMID 29654803›Full record

ArticleHuman immunology2018

Donor cell chimerism evaluation in cerebrospinal fluid by short tandem repeat analysis following allogeneic hematopoietic stem cell transplantation.

Jessica L Spruit, Omar R Fagoaga, Süreyya Savaşan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jessica L SpruitPediatric Blood and Marrow Transplantation, Children's Hospital of Michigan, 3901 Beaubien, Detroit, MI 48201, USA. Electronic address: aq6019@wayne.edu.
Omar R FagoagaHistocompatibility and Immunogenetics Lab, DMC University Laboratories, Hutzel/KEI Building, 4707 Saint Antoine Street, Detroit, MI 48201, USA; Wayne State University School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA. Electronic address: ofagoa@dmc.org.
Süreyya SavaşanPediatric Blood and Marrow Transplantation, Children's Hospital of Michigan, 3901 Beaubien, Detroit, MI 48201, USA; Wayne State University School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA; Barbara Ann Karmanos Cancer Center, 4100 John R Street, Detroit, MI 48201, USA. Electronic address: ssavasan@med.wayne.edu.
Children's Hospital of Michigan · USWayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
NCI NIH HHS P30 CA022453
6 · The paper itself

Abstract

Cerebrospinal fluid (CSF) cell count, morphology and flow cytometric evaluations are used to investigate central nervous system (CNS) involvement in leukemia/lymphoma. We performed CSF short tandem repeat (STR) analysis to monitor CSF chimerism status and evaluate for disease involvement in 11 asymptomatic pediatric allogeneic hematopoietic stem cell transplantation (HSCT) recipients with hemato-lymphoid neoplasms and high risk for or history of CNS involvement. Eighteen (64%) of the samples with median CSF cell count of 1/mm

Indexed as

Hematopoietic Stem Cell TransplantationCerebrospinal FluidChildChimerismFemaleHematologic NeoplasmsHumansLymphocyte CountLymphocytesMaleMicrosatellite RepeatsTransplantation ChimeraTransplantation ConditioningTransplantation, HomologousCerebrospinal fluidDonor chimerismHematopoietic stem cell transplantationShort tandem repeat analysis

Identifiers

PMID29654803
PMCPMC6854661
OpenAlexW2797775851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.