Trial reportEuropean radiology2018
Assessment of an advanced virtual monoenergetic reconstruction technique in cerebral and cervical angiography with third-generation dual-source CT: Feasibility of using low-concentration contrast medium.
Trial report in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Optimization of head and neck vascular CT angiography using variable rate bolus tracking technique and third-generation dual-source CT dual-energy scanning.BMC medical imaging · 2025Article
- Improving visualization of free fibula flap perforators and reducing radiation dose in dual-energy CT angiography.Quantitative imaging in medicine and surgery · 2023Article
- Advanced virtual monoenergetic imaging algorithm for lower extremity computed tomography angiography: effects on image quality, artifacts, and peripheral arterial disease evaluationDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Noise-optimized virtual monoenergetic imaging technology of the third-generation dual-source computed tomography and its clinical applications.Quantitative imaging in medicine and surgery · 2021Review
- Generally applicable window settings of low-keV virtual monoenergetic reconstructions in dual-layer CT-angiography of the head and neck.Quantitative imaging in medicine and surgery · 2021Article
- Fistula from right and left coronary arteries to pulmonary artery: Coronary CT angiography and coronary angiography findings.Radiology case reports · 2021Article
- Objective and subjective comparison of virtual monoenergetic vs. polychromatic images in patients with pancreatic ductal adenocarcinoma.European radiology · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesTo investigate the feasibility of low-concentration contrast media (LC-CM) in cerebral and cervical dual-energy CT angiography (DE-CTA) using an advanced monoenergetic (Mono+) reconstruction technique.
methodsSixty-five consecutive patients prospectively selected to undergo cerebral and cervical DE-CTA were randomised into two groups: 32 patients (63.7 ± 9.7 years) in the high-concentration contrast medium (HC-CM) group with iopromide 370 and 33 patients (60.7 ± 10.8 years) in the low-concentration contrast medium (LC-CM) group with iodixanol 270. Traditional monoenergetic (Mono) and Mono+ images from 40 to 100 keV levels (at 10-keV intervals) and the standard mixed (Mixed, 120 kVp equivalent) images were reconstructed. Subjective image quality parameters included the contrast-to-noise ratio (CNR) and objective image quality parameters were evaluated and compared between the two groups.
resultsThe 40-keV Mono+ images in the LC-CM group showed comparable objective CNR (common carotid arteries: 83.7 ± 24.5 vs. 78.1 ± 23.2; internal carotid arteries: 82.2 ± 26.8 vs. 76.8 ± 24.1; middle cerebral arteries: 72.5 ± 24.6 vs. 70.6 ± 19.2; all p > 0.05) and subjective image scores (3.95 ± 0.19 vs. 3.83 ± 0.35; p > 0.05) compared with Mixed images in the HC-CM group.
conclusionThe Mono+ reconstruction technique could reduce the concentration of iodinated CM in the diagnosis of cerebral and cervical angiography. KEY POINTS: • Mono+ shows decreased noise and superior CNR compared with Mono. • The 40-keV Mono+ images show the highest CNR in the LC-CM group. • The Mono+ reconstruction technique could reduce the concentration of iodinated CM.
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