Evidence map›Paper›PMID 29654559›Full record

ArticleEuropean radiology2018

Volumetric dynamic oxygen-enhanced MRI (OE-MRI): comparison with CT Brody score and lung function in cystic fibrosis patients.

K Martini, C M Gygax, C Benden, A R Morgan, G J M Parker, T Frauenfelder

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Advances in imaging for lung emphysema.Annals of translational medicine · 2020
    Review
  9. Article
  10. Review
  11. The future of cystic fibrosis care: a global perspective.The Lancet. Respiratory medicine · 2020
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

K MartiniInstitute for Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. katharina.martini@usz.ch.
C M GygaxUniversity of Zurich, Zurich, Switzerland.
C BendenDivision of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
A R MorganBioxydyn Limited, Manchester, UK.
G J M ParkerBioxydyn Limited, Manchester, UK.
T FrauenfelderInstitute for Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.

Funding

Swiss lung association (Lungenliga Schweiz) NA
6 · The paper itself

Abstract

objectivesTo demonstrate, in patients with cystic fibrosis (CF), the correlation between three-dimensional dynamic oxygen-enhanced magnetic resonance imaging (OE-MRI) measurements and computed tomography Brody score (CF-CT) and lung function testing (LFT).

methodsTwenty-one patients (median age, 25 years; female, n = 8) with a range of CF lung disease and five healthy volunteers (median age, 31 years; female, n = 2) underwent OE-MRI performed on a 1.5-T MRI scanner. Coronal volumes were acquired while patients alternately breathed room air and 100% oxygen. Pre-oxygen T

resultsMean CF-CT was 24.1±17.1. Mean ΔPO

conclusionsFunctional lung imaging using OE-MRI has the capability to assess the severity of CF lung disease and shows a significant correlation with LFT and CF-CT. KEY POINTS: • Oxygen-enhanced MRI might play a future role in evaluation and follow-up of cystic fibrosis. • Heterogeneity of parameter maps reflects localised functional impairment in cystic fibrosis. • Avoidance of cumulative radiation burden in CF is feasible using OE-MRI.

Indexed as

AdultCase-Control StudiesCystic FibrosisFemaleHealthy VolunteersHumansImaging, Three-DimensionalLungLung DiseasesMagnetic Resonance ImagingMaleOxygenRespiratory Function TestsTomography, X-Ray ComputedYoung AdultOxygenCystic fibrosisLungLung diseaseMagnetic resonance imagingMRI

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.