Evidence map›Paper›PMID 29654422›Full record

Trial reportLasers in medical science2018

Removal of unwanted hair: efficacy, tolerability, and safety of long-pulsed 755-nm alexandrite laser equipped with a sapphire handpiece.

Steven Paul Nistico, Ester Del Duca, Francesca Farnetani, Stefania Guida, Giovanni Pellacani, Ali Rajabi-Estarabadi, Keyvan Nouri

Open access · greenAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Applications of Long-Pulse Alexandrite Laser in Cosmetic Dermatology: A Review.Clinical, cosmetic and investigational dermatology · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Lasers for Becker's nevus.Lasers in medical science · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Steven Paul NisticoDepartment of Health Sciences, University of Catanzaro "Magna Graecia", Viale Europa, Germaneto, 88100, Catanzaro, Italy. steven.nistico@gmail.com.
Ester Del DucaUniversity of Tor Vergata, Rome, Italy.
Francesca FarnetaniDepartment of Dermatology, University of Modena, Modena, Italy.
Stefania GuidaDepartment of Dermatology, University of Modena, Modena, Italy.
Giovanni PellacaniDepartment of Dermatology, University of Modena, Modena, Italy.
Ali Rajabi-EstarabadiDepartment of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Keyvan NouriDepartment of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
University of Modena and Reggio Emilia · ITUniversity of Miami · USMagna Graecia University · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the difference in refraction coefficients between air and the corneal epithelium, irradiation of the skin with a light source can lead to reflection of the energy and its leakage to the skin causes epidermal injury. All of which decreases the efficacy of treatment. We evaluated cooling sapphire handpieces' efficacy in decreasing pain and epidermal injuries and enhancing the treatment outcome in laser hair removal. A total of 49 patients with Fitzpatrick skin types of II to IV were treated for laser hair removal on face, limbs, inguinal, and axillary areas with pulsed 755-nm alexandrite laser equipped with a sapphire handpiece and the cooling system. Hair counts were performed by two independent observers at the baseline and 3 months after the final treatment. A marked reduction in hair regrowth was noted 3 months after the final treatment in all body locations studied. Clinical hair reduction was observed and fully assessed. There were no serious side effects with an average pain score of 4.6 out of 40. The cooled sapphire cylinder tip has been shown to minimize epidermal injury and reduce the system energy leaks to the skin.

Indexed as

AdultAluminum OxideBerylliumFemaleFollow-Up StudiesHairHair RemovalHumansLasers, Solid-StateMalePatient SatisfactionTreatment OutcomeYoung AdultalexandriteAluminum OxideBeryllium755 nmAlexandriteHair removalLaser

Identifiers

PMID29654422
OpenAlexW2797841142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.