Evidence map›Paper›PMID 29654324›Full record

ArticleScientific reports2018

Integrated dual-tomography for refractive index analysis of free-floating single living cell with isotropic superresolution.

Vinoth B, Xin-Ji Lai, Yu-Chih Lin, Han-Yen Tu, Chau-Jern Cheng

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vinoth BInstitute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei, 11677, Taiwan.
Xin-Ji LaiInstitute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei, 11677, Taiwan.
Yu-Chih LinInstitute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei, 11677, Taiwan.
Han-Yen TuDepartment of Electrical Engineering, Chinese Culture University, Taipei, 11114, Taiwan.
Chau-Jern ChengInstitute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei, 11677, Taiwan. cjcheng@ntnu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Digital holographic microtomography is a promising technique for three-dimensional (3D) measurement of the refractive index (RI) profiles of biological specimens. Measurement of the RI distribution of a free-floating single living cell with an isotropic superresolution had not previously been accomplished. To the best of our knowledge, this is the first study focusing on the development of an integrated dual-tomographic (IDT) imaging system for RI measurement of an unlabelled free-floating single living cell with an isotropic superresolution by combining the spatial frequencies of full-angle specimen rotation with those of beam rotation. A novel 'UFO' (unidentified flying object) like shaped coherent transfer function is obtained. The IDT imaging system does not require any complex image-processing algorithm for 3D reconstruction. The working principle was successfully demonstrated and a 3D RI profile of a single living cell, Candida rugosa, was obtained with an isotropic superresolution. This technology is expected to set a benchmark for free-floating single live sample measurements without labeling or any special sample preparations for the experiments.

Indexed as

AlgorithmsImage Processing, Computer-AssistedImaging, Three-DimensionalRefractometrySingle-Cell AnalysisTomography

Identifiers

PMID29654324
PMCPMC5899089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.