ArticleNature communications2018
Gold nanocrystal-mediated sliding of doublet DNA origami filaments.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A programmable DNA origami nanosyringe for directed membrane translocation.Nature nanotechnology · 2026Article
- Review
- Engineering DNA-based cytoskeletons for synthetic cells.Interface focus · 2023Review
- Application and prospects of nucleic acid nanomaterials in tumor therapy.RSC advances · 2023Review
- PhotocleavableChemical reviews · 2023Review
- Recent Advances in DNA Origami-Engineered Nanomaterials and Applications.Chemical reviews · 2023Review
- Three-phase DNA-origami stepper mechanism based on multi-leg interactions.Biophysical journal · 2022Article
- Article
- Dimerization and oligomerization of DNA-assembled building blocks for controlled multi-motion in high-order architectures.Nature communications · 2021Article
- DNA Origami-Enabled Plasmonic Sensing.The journal of physical chemistry. C, Nanomaterials and interfaces · 2021Review
- Robotic DNA Nanostructures.ACS synthetic biology · 2020Review
- Dynamic DNA Assemblies in Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Dynamic Actuation of DNA-Assembled Plasmonic Nanostructures in Microfluidic Cell-Sized Compartments.Nano letters · 2020Article
- A rotary plasmonic nanoclock.Nature communications · 2019Article
- DNA-assembled nanoarchitectures with multiple components in regulated and coordinated motion.Science advances · 2019Article
- DNA-Assembled Multilayer Sliding Nanosystems.Nano letters · 2019Article
- Mastering Complexity: Towards Bottom-up Construction of Multifunctional Eukaryotic Synthetic Cells.Trends in biotechnology · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sliding is one of the fundamental mechanical movements in machinery. In macroscopic systems, double-rack pinion machines employ gears to slide two linear tracks along opposite directions. In microscopic systems, kinesin-5 proteins crosslink and slide apart antiparallel microtubules, promoting spindle bipolarity and elongation during mitosis. Here we demonstrate an artificial nanoscopic analog, in which gold nanocrystals can mediate coordinated sliding of two antiparallel DNA origami filaments powered by DNA fuels. Stepwise and reversible sliding along opposite directions is in situ monitored and confirmed using fluorescence spectroscopy. A theoretical model including different energy transfer mechanisms is developed to understand the observed fluorescence dynamics. We further show that such sliding can also take place in the presence of multiple DNA sidelocks that are introduced to inhibit the relative movements. Our work enriches the toolbox of DNA-based nanomachinery, taking one step further toward the vision of molecular nanofactories.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.