Evidence map›Paper›PMID 29654295›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2018

Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice.

Ines Armando, Laureano D Asico, Xiaoyan Wang, John E Jones, Maria Paula Serrão, Santiago Cuevas, David K Grandy, Patricio Soares-da-Silva, Pedro A Jose

Open access · greenAbstract read
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  3. Effect of DCardiology discovery · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ines ArmandoDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA. iarmando@gwu.edu.
Laureano D AsicoDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA.
Xiaoyan WangDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA.
John E JonesDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA.
Maria Paula SerrãoMedInUP - Center for Drug Discovery and Innovative Medicines, University of Porto, 4200-319, Porto, Portugal.
Santiago CuevasDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA.
David K GrandyDepartment of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR, 97239, USA.
Patricio Soares-da-SilvaMedInUP - Center for Drug Discovery and Innovative Medicines, University of Porto, 4200-319, Porto, Portugal.
Pedro A JoseDepartment of Medicine, Division of Renal Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20057, USA.
George Washington University · USUniversidade do Porto · PTOregon Health & Science University · US

Funding

RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
GRK4 & Development of Salt SensitivityR01HL092196 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES, JOSE, PEDRO A. · 2008 to 2017
$3.6M
RENAL DOPAMINE RECEPTOR REGULATION AND FUNCTIONR01HL023081 · NHLBI · GEORGETOWN UNIVERSITY · PI JOSE, PEDRO A. · 1985 to 2006
$2.4M
Role of Dopamine D2 Receptor in Renal Inflammation and InjuryR01DK090918 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES · 2011 to 2015
$1.7M
NHLBI NIH HHS R01 HL023081NHLBI NIH HHS R01 HL092196NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK090918
6 · The paper itself

Abstract

Abnormalities of the D

Indexed as

AnimalsAntihypertensive AgentsBenzopyransBlood PressureDopamineHypertensionImidazolesKidneyMiceMice, KnockoutNorepinephrineOxidative StressReactive Oxygen SpeciesReceptors, Dopamine D2Antihypertensive AgentsBenzopyransDopamineetamicastatImidazolesNorepinephrineReactive Oxygen SpeciesReceptors, Dopamine D2

Identifiers

PMID29654295
PMCPMC6503839
OpenAlexW2799530220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.